Low humidity enhances thermotolerance in Caenorhabditis elegans .
| Autor: | Brown ME; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States., Hernandez-Urbina DA; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States., Kumsta C; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, United States. |
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| Jazyk: | angličtina |
| Zdroj: | MicroPublication biology [MicroPubl Biol] 2024 Nov 23; Vol. 2024. Date of Electronic Publication: 2024 Nov 23 (Print Publication: 2024). |
| DOI: | 10.17912/micropub.biology.001404 |
| Abstrakt: | Humidity is an important environmental factor that causes physiological changes in organisms. In humans, high humidity disrupts thermoregulation by limiting heat dissipation, leading to heat stress. While Caenorhabditis elegans lacks comparable thermoregulatory systems, humidity may still impact its heat tolerance by affecting cellular stress responses. We tested this by subjecting C. elegans to heat shock under different humidity conditions and found that lower humidity during heat shock improved survival compared to higher humidity. These findings demonstrate that humidity is an important variable affecting thermotolerance in C. elegans and should be standardized in heat-stress experiments. Competing Interests: The authors declare that there are no conflicts of interest present. (Copyright: © 2024 by the authors.) |
| Databáze: | MEDLINE |
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