Drosophila kikkawai ortholog of the D. melanogaster Muller D element ash1 .

Autor:	Mo M; Washington University in St. Louis, St. Louis, Missouri, United States., Sabb D; New Jersey City University, Jersey City, New Jersey, United States., LoBello L; Washington University in St. Louis, St. Louis, Missouri, United States., Chambers K; Mercer University, Macon, Georgia, United States., Kershaw K; St. Joseph's University, Philadelphia, Pennsylvania, United States., Welles C; University of the Fraser Valley, Abbotsford, British Columbia, Canada., Kurucz J; University of the Fraser Valley, Abbotsford, British Columbia, Canada., Rhyne C; Mercer University, Macon, Georgia, United States., Nichols A; Mercer University, Macon, Georgia, United States., Stanga J; Biology, Mercer University, Macon, Georgia, United States., Bedard JEJ; Biology, University of the Fraser Valley, Abbotsford, British Columbia, Canada., Arrigo C; Biology, New Jersey City University, Jersey City, New Jersey, United States.
Jazyk:	angličtina
Zdroj:	MicroPublication biology [MicroPubl Biol] 2024 Nov 22; Vol. 2024. Date of Electronic Publication: 2024 Nov 22 (Print Publication: 2024).
DOI:	10.17912/micropub.biology.001322
Abstrakt:	The Drosophila kikkawai feature with Gene ID 108083276 was determined to be an ortholog of Drosophila melanogaster absent, small, or homeotic discs 1 ( ash1 ). Two isoforms, ash1-PB and ash1-PC, were constructed on the D. kikkawai Muller D element using the GEP annotation protocol. The second coding exon of D. kikkawai ash1 includes an insertion translated into 18 additional amino acids compared to the D. melanogaster protein and is supported by RNA-Seq coverage, the lack of splice junction predictions, and multiple gene predictors. The first intron in both isoforms of D. kikkawaiash1 contains a well conserved non-canonical GC splice site. Competing Interests: The authors declare that there are no conflicts of interest present. (Copyright: © 2024 by the authors.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu