Intracranial aneurysm coexisting with pituitary adenoma: a systematic review.
Autor: | de Sena Barbosa MG; Department of Neurosurgery, Atenas University Center, Passos, MG, Brazil., Otávio da Silva V; Department of Neurosurgery, Atenas University Center, Passos, MG, Brazil., Santos Ferreira LH; Department of Neurosurgery, Atenas University Center, Paracatu, MG, Brazil., de Souza RLV; Department of Neurosurgery, Atenas University Center, Passos, MG, Brazil., Pipek LZ; School of Medicine, University of São Paulo (FMUSP), São Paulo SP, Brazil, Hospital das Clínicas / FMUSP., de Oliveira Almeida G; Department of Neurosurgery, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil., Figueiredo EG; Division of Neurosurgery, School of Medicine, University of São Paulo (FMUSP), São Paulo SP, Brazil, Hospital das Clínicas / FMUSP., Rabelo NN; Division of Neurosurgery, School of Medicine, University of São Paulo (FMUSP), São Paulo SP, Brazil, Hospital das Clínicas / FMUSP., Chaurasia B; Department of Neurosurgery, Neurosurgery Clinic, Birgunj, Nepal. |
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Jazyk: | angličtina |
Zdroj: | Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 Oct 25; Vol. 86 (12), pp. 7232-7237. Date of Electronic Publication: 2024 Oct 25 (Print Publication: 2024). |
DOI: | 10.1097/MS9.0000000000002692 |
Abstrakt: | Introduction: The simultaneous occurrence of intracranial aneurysms (IA) and primary brain tumors (BT) is frequently reported, with an estimated incidence of 0.5-7.4%. Among the tumor types associated with IA, pituitary adenomas (PA) are the most prevalent. Methods: The authors selected articles, published from 1960 to December 2023, on the Medline, Embase, Scopus, Cochrane Library, and Web of Science databases. The extraction form contains information specific to the aneurysm and tumor, rupture of the aneurysm, treatment proposal for both and order of treatment and outcome. Results: The study evaluated 118 patients from 25 articles. The most frequent types of tumors were non-functioning hormone (NFA) producers, present in 45.8% ( n =54) of the cases, and growth hormone (GH) secretors, which represent 23.0% ( n =27) of the cases. The main treatment used was surgery, with subtotal resection (STR) performed in 4.2% ( n =5) of cases, gross total resection (GTR) in 3.4% ( n =4), and transsphenoidal resection (TSR) in 7.6% ( n =9). 16.0% ( n =19) of patients had two or more aneurysms concomitant with the adenoma. IA treatment was performed before PA surgery in 25 patients (21.2%) and 15 patients received simultaneous treatment to IA and PA (12.7%). Conclusion: Patients with PAs have a considerable prevalence of IAs. Hormonal imbalances and mechanical changes induced by tumor growth, particularly influenced by GH and IGF-1, contribute to this coexistence. Surgical intervention is common, requiring meticulous precautions to avoid complications. More longitudinal studies including close follow-up with a description of outcomes are necessary to guide treatment protocols for this condition. Competing Interests: The authors declare no conflicts of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.) |
Databáze: | MEDLINE |
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