Cambridge risk score, new hyperglycemia, and complications in surgical patients without diabetes.

Autor: Lee H; Department of Internal Medicine, Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address: hlee@mcw.edu., Hartfield PJ; Department of Internal Medicine, Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA., Thorgerson A; Center for Advancing Population Science (CAPS), Medical College of Wisconsin, Milwaukee, WI, USA., Sinson GP; Department of Neurosurgery, Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA., Wang M; Department of Neurosurgery, Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA., Mendez CE; Department of Internal Medicine, Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA.
Jazyk: angličtina
Zdroj: Journal of diabetes and its complications [J Diabetes Complications] 2025 Jan; Vol. 39 (1), pp. 108926. Date of Electronic Publication: 2024 Dec 05.
DOI: 10.1016/j.jdiacomp.2024.108926
Abstrakt: Aims: Our study examined the association between the Cambridge Risk Score (CRS), new hyperglycemia (NH), and complications in patients undergoing elective surgery.
Methods: In this retrospective cross-sectional study, adult surgical patients, without diabetes, with NH (blood glucose ≥140 mg/dL) were identified, and the CRS was calculated. We used univariate regression models to evaluate the relationship between CRS and NH with 30-day readmission, length of stay (LOS), and complications. Models were stratified by surgical specialty (cardiac/vascular, general, orthopedic, neurologic).
Results: Of 10,531 patients in the study, 24 % had NH. After adjusting for covariates, the CRS was associated with increased odds of complications [OR 2.09; 95%CI:1.69, 2.59] and NH [OR 1.95; 95%CI:1.66, 2.29]. NH was associated with increased odds of 30-day readmission [β 1.60; 95%CI:1.31, 1.96], and increased LOS [β 0.64; 95%CI:0.59, 0.68]. When stratified by surgery type, the CRS was associated with increased LOS in neurosurgery, decreased LOS in orthopedics, and increased odds of complications and NH in neurosurgery and orthopedics.
Conclusion: The CRS is associated with NH, complications, and LOS in patients undergoing elective neurosurgery, orthopedic surgery, and general surgery. This suggests that CRS may have potential to help identify surgical patients at high risk for NH and complications.
Competing Interests: Declaration of competing interest The authors declare that there is no conflict of interest.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE