Prognostic implication of sarcopenia diagnosed by updated Asian Working Group for Sarcopenia criteria in older patients with heart failure: Utility and limitation.

Autor:	Katano S; Division of Rehabilitation, Sapporo Medical University Hospital, Sapporo, Japan; Second Division of Physical Therapy, Sapporo Medical University School of Health Science, Sapporo, Japan. Electronic address: s.katano@sapmed.ac.jp., Yamano K; Division of Rehabilitation, Sapporo Medical University Hospital, Sapporo, Japan; Second Division of Physical Therapy, Sapporo Medical University School of Health Science, Sapporo, Japan., Yano T; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo Japan. Electronic address: tyano@sapmed.ac.jp., Numazawa R; Graduate School of Medicine, Sapporo Medical University, Sapporo, Japan., Nagaoka R; Division of Rehabilitation, Sapporo Medical University Hospital, Sapporo, Japan; Graduate School of Medicine, Sapporo Medical University, Sapporo, Japan., Honma S; Graduate School of Medicine, Sapporo Medical University, Sapporo, Japan; Department of Rehabilitation, Sapporo Cardiovascular Hospital, Sapporo, Japan., Fujisawa Y; Second Division of Physical Therapy, Sapporo Medical University School of Health Science, Sapporo, Japan; Department of Rehabilitation, Japanese Red Cross Asahikawa Hospital, Asahikawa, Japan., Miki Y; Department of Rehabilitation, Hakodate Goryokaku Hospital, Hakodate, Japan., Takamura Y; Department of Rehabilitation, Sapporo Kojinkai Memorial Hospital, Sapporo, Japan., Kunihara H; Division of Rehabilitation, Sapporo Medical University Hospital, Sapporo, Japan., Fujisaki H; Division of Rehabilitation, Sapporo Medical University Hospital, Sapporo, Japan., Kouzu H; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo Japan., Ohori K; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo Japan; Department of Cardiology, Hokkaido Cardiovascular Hospital, Sapporo, Japan., Katayose M; Division of Rehabilitation, Sapporo Medical University Hospital, Sapporo, Japan; Second Division of Physical Therapy, Sapporo Medical University School of Health Science, Sapporo, Japan., Hashimoto A; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo Japan; Division of Health Care Administration and Management, Sapporo Medical University School of Medicine, Sapporo, Japan., Furuhashi M; Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo Japan.
Jazyk:	angličtina
Zdroj:	The journal of nutrition, health & aging [J Nutr Health Aging] 2024 Dec 05; Vol. 29 (1), pp. 100434. Date of Electronic Publication: 2024 Dec 05.
DOI:	10.1016/j.jnha.2024.100434
Abstrakt:	Objectives: The utility of the updated Asian Working Group for Sarcopenia (AWGS) criteria in diagnosing sarcopenia in older patients with heart failure (HF) remains unclear. Objective: To analyze the prevalence and prognostic impact of sarcopenia diagnosed by the updated AWGS criteria in older patients with HF. Design: Ambispective cohort study. Setting & Subjects: 534 older patients with HF from a university hospital in Japan. Measurements: Sarcopenia was assessed using different versions of the AWGS criteria: AWGS 2014, AWGS 2019H (muscle mass relative to height squared), and AWGS 2019B (muscle mass relative to BMI). The primary endpoint was all-cause mortality at three years post-discharge. Results: Of 534 patients, 42%, 57%, and 44% were diagnosed with sarcopenia according to AWGS 2014, AWGS 2019H, AWGS 2019B, respectively. Among patients without AWGS 2014-defined sarcopenia, 23% were reclassified as having sarcopenia by AWGS 2019H criteria. Forty-four percent of sarcopenic patients diagnosed by AWGS 2019H were re-classified as non-sarcopenic by AWGS 2019B, with lower fat mass and poorer nutritional status. After the multivariate Cox proportional hazard analyses, an association between all-cause death and sarcopenia remained significant for AWGS 2014 (hazard ratio [HR], 1.55; 95% confidence interval [CI], 1.01-2.37) and AWGS 2019H (HR, 1.65; 95% CI, 1.05-2.59), but not for AWGS 2019B (HR, 0.99; 95% CI, 0.64-1.51). Conclusion: The updated AWGS 2019H criteria detected more sarcopenic patients with HF while maintaining favorable predictive ability. The use of BMI-adjusted muscle mass reclassified underweight and malnourished patients as non-sarcopenic, limiting its impact on the mortality prediction in older patients with HF. (Copyright © 2024 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)
Databáze:	MEDLINE
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