A rare case of cerebellar abscess caused by Nocardia cyriacigeorgica .

Autor:	Koruga N; Department of Neurosurgery, University Hospital Center Osijek, Osijek, Croatia.; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia., Reljac G; Department of Neurosurgery, University Hospital Center Osijek, Osijek, Croatia., Rončević A; Department of Neurosurgery, University Hospital Center Osijek, Osijek, Croatia.; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia., Bogdan M; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Microbiology, Parasitology and Clinical Laboratory Diagnostics, University Hospital Center, Osijek, Croatia., Sabadi D; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department ofInfectious Diseases, University Hospital Center Osijek, Osijek, Croatia., Farčić N; Department of Neurosurgery, University Hospital Center Osijek, Osijek, Croatia.; Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia., Rotim T; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Diagnostic and Interventional Radiology, University Hospital Center Osijek, Osijek, Croatia., Turk T; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Diagnostic and Interventional Radiology, University Hospital Center Osijek, Osijek, Croatia., Rončević R; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Diagnostic and Interventional Radiology, University Hospital Center Osijek, Osijek, Croatia., Soldo Koruga A; Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Neurology, University Hospital Center Osijek, Osijek, Croatia., Dmitrović B; Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Pathology and Forensic Medicine, University Hospital Center Osijek, Osijek, Croatia.
Jazyk:	angličtina
Zdroj:	Surgical neurology international [Surg Neurol Int] 2024 Nov 15; Vol. 15, pp. 413. Date of Electronic Publication: 2024 Nov 15 (Print Publication: 2024).
DOI:	10.25259/SNI_426_2024
Abstrakt:	Background: Gram-positive opportunistic bacteria of the Nocardia species are responsible for a large spectrum of infections, such as pneumonia, skin infections, and more widespread conditions, including brain abscesses. Case Description: A 67-year-old male patient suffered from headache, gait disorder, and vertigo for a week before admission to our department. An enhanced magnetic resonance imaging scan revealed a mediosagittal hyperintense infratentorial lesion with concomitant compression of the fourth ventricle. The patient underwent surgical treatment with general anesthesia. The frozen section did not reveal any tumoral tissue but rather a purulent content. He was comatose on the 1 st postoperative day, and he underwent a follow-up computed tomography (CT) scan, which revealed triventricular hydrocephalus. The external ventricular drain was performed, and a follow-up CT scan revealed significant improvement of hydrocephalus. Matrix-Assisted Laser Desorption Ionization Time of Flight did not reveal any causative agent from the intraoperative content, but the 16s ribosomal DNA method confirmed Nocardia cyriacigeorgica . The patient was intravenously treated with ceftriaxone and trimethoprim/sulfamethoxazole and died on the 5 th postoperative day. Conclusion: Nocardiosis presents a rare Gram-positive bacterial infection that typically affects immunocompromised hosts. Nocardia -caused brain abscesses present a significant challenge in its treatment for its atypical presentation and slow culture growth. Competing Interests: There are no conflicts of interest. (Copyright: © 2024 Surgical Neurology International.)
Databáze:	MEDLINE
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