Minoxidil Intoxication: A Case of Refractory Shock With Prolonged Supportive Care.
| Autor: | Maigre S; Emergency Department, Centre Hospitalier Universitaire Tivoli, La Louvière, BEL., Meurant V; Emergency Department, Centre Hospitalier Universitaire Tivoli, La Louvière, BEL. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Nov 04; Vol. 16 (11), pp. e73019. Date of Electronic Publication: 2024 Nov 04 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.73019 |
| Abstrakt: | Minoxidil, commonly used as a topical agent for alopecia, is occasionally used for refractory hypertension due to its antihypertensive properties. We report a rare case of massive minoxidil intoxication leading to refractory vasoplegic shock in a 24-year-old male. The patient ingested 120 mL of 5% minoxidil solution, resulting in vasoplegic shock. Management included fluid resuscitation and norepinephrine support. The patient required norepinephrine for 180 hours to maintain mean arterial pressure, a duration unprecedented in the literature. This case underscores the potential for prolonged vasopressor dependency following massive minoxidil ingestion and highlights the necessity for intensive symptomatic management. This report adds to the limited literature on minoxidil intoxication and suggests that extensive supportive care can be prolonged. Competing Interests: Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Maigre et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|