Synovial sarcoma masquerading as juvenile idiopathic arthritis.

Autor: Mukherjee S; Clinical Immunology and Rheumatology, King George's Medical University, Lucknow, Uttar Pradesh, India drsayanmukherjee90@gmail.com., Kumar P; Clinical Immunology and Rheumatology, King George's Medical University, Lucknow, Uttar Pradesh, India., Maurya MK; Clinical Immunology and Rheumatology, King George's Medical University, Lucknow, Uttar Pradesh, India., Kumar P; Clinical Immunology and Rheumatology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2024 Dec 05; Vol. 17 (12). Date of Electronic Publication: 2024 Dec 05.
DOI: 10.1136/bcr-2024-262146
Abstrakt: An early adolescent girl presented with chronic deforming monoarthritis. Initially misdiagnosed with skeletal tuberculosis, she received empirical treatment despite the absence of microbiological evidence. Her symptoms were managed intermittently with non-steroidal anti-inflammatory drugs, but the persistence and progression of her condition over the past 4 months raised suspicions of juvenile idiopathic arthritis. Her clinical presentation deteriorated, with severe knee arthritis and rapid calf swelling, prompting differential diagnosis including necrotising fasciitis or a ruptured Baker's cyst. Imaging confirmed synovitis with localised necrotising myositis, while persistent pain after fascial release and systemic inflammation without signs of infection indicated a more sinister underlying condition. Histopathological analysis of the biopsied tissue revealed synovial sarcoma, with subsequent PET-CT confirming skeletal and pulmonary metastasis. Despite timely diagnosis, the patient ultimately succumbed to her illness.
Competing Interests: Competing interests: None declared.
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Databáze: MEDLINE