SMILE and ICL implantation on the ocular surface and meibomian glands in patients with postoperative myopia.

Autor: Yao J; Department of Ophthalmology, Taiyuan Central Hospital, Taiyuan, Shanxi Province, 030009, China. docyaojuan@163.com.; The Ninth Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China. docyaojuan@163.com., Feng J; Department of Ophthalmology, Taiyuan Central Hospital, Taiyuan, Shanxi Province, 030009, China.; The Ninth Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China., Li W; Department of Ophthalmology, Taiyuan Central Hospital, Taiyuan, Shanxi Province, 030009, China.; The Ninth Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China., Liu C; Department of Ophthalmology, Taiyuan Central Hospital, Taiyuan, Shanxi Province, 030009, China.; The Ninth Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China., Li Y; Department of Ophthalmology, Taiyuan Central Hospital, Taiyuan, Shanxi Province, 030009, China.; The Ninth Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China., Wang X; Department of Ophthalmology, Eye, Ear, Nose & Throat Hospital of Fudan University, No. 19 BaoQing Road, Shanghai, 200031, China. xiaoyingbbb@163.com.
Jazyk: angličtina
Zdroj: BMC ophthalmology [BMC Ophthalmol] 2024 Dec 04; Vol. 24 (1), pp. 522. Date of Electronic Publication: 2024 Dec 04.
DOI: 10.1186/s12886-024-03790-2
Abstrakt: Background: Objectively compare the changes in ocular surface parameters in myopic patients who have undergone either SMILE or Implantable Collamer Lens (ICL V4c) surgery.
Methods: This prospective cohort study enrolled 32 patients (32 eyes) undergoing SMILE surgery and 35 patients (35 eyes) receiving ICL V4c intraocular lenses. Examinations were performed at preoperative, 1-week, 1-month, and 3-month postoperative time points. The assessments included Schirmer's I Test (SIt), First Non-Invasive Break-Up Time (First-NIBUT), Average Non-Invasive Break-Up Time (Average-NIBUT), Tear Meniscus Height (TMH), Ocular Surface Disease Index (OSDI) score, conjunctival congestion score, meibomian gland loss score, lipid layer analysis score, lid margin opening detection score, and corneal fluorescein staining (CFS) score.
Results: Repeated measures ANOVA revealed that SIT, TMH, and First-NIBUT initially decreased and then increased. At three months, SIT levels in the SMILE group were significantly lower than those in the ICL group. From the first month onward, TMH levels in the SMILE group remained significantly lower than those in the ICL group (P < 0.05). OSDI scores initially rose and then fell, with the SMILE group consistently showing higher OSDI levels than the ICL group. Conjunctival congestion scores in the SMILE group fluctuated less, while the ICL group exhibited a clear downward trend, with significant differences starting from the first week (P < 0.05). Over time, scores for meibomian gland loss, lipid layer analysis, and lid margin opening detection were all higher in the SMILE group compared to the ICL group.
Conclusions: SMILE surgery has a more pronounced and prolonged impact on the ocular surface and meibomian gland function compared to ICL implantation. Objective dry eye parameters in the ICL group recover more quickly than those in the SMILE group one month post-surgery.
Competing Interests: Declarations. Ethics approval and consent to participate: The study was conducted in accordance with the Declaration of Qelsinki, and approved by the Ethics Committee of Taiyuan Central Hospital.Written informed consent was obtained from all patients after the nature and possible consequences of the study were explained. Clinical trial number: Not applicable. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s).)
Databáze: MEDLINE
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