Development of Nanomaterials-Based Agents for Selective Antibacterial Activity.

Autor: Kaur N; Department of Organic Chemistry, Indian Institute of Science, Bangalore, 560012, India., Sahoo J; Department of Organic Chemistry, Indian Institute of Science, Bangalore, 560012, India., De M; Department of Organic Chemistry, Indian Institute of Science, Bangalore, 560012, India.
Jazyk: angličtina
Zdroj: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Dec 05, pp. e202400693. Date of Electronic Publication: 2024 Dec 05.
DOI: 10.1002/cbic.202400693
Abstrakt: Bacterial infections continue to threaten public health due to limitations in rapid and accurate diagnostic techniques. While broad-spectrum antibiotics offer empirical treatment, their overuse has fuelled the emergence of antimicrobial resistance (AMR) pathogens, posing a critical global public health challenge. In this critical scenario, nanomaterial-based antibacterial agents emerge as a promising solution to combat bacteria and inhibit their proliferation. However, selective elimination of pathogenic bacteria is paramount. This review highlights recent advancements in developing nanomaterials for selective antibacterial activity. We categorize these agents based on their mode of action, exploring how they selectively interact with bacteria and their potential antibacterial mechanisms. This review offers crucial insights for researchers exploring the potential of nanotechnology to address the growing threat of AMR.
(© 2024 Wiley-VCH GmbH.)
Databáze: MEDLINE
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