| Autor: |
Cheong D; Medical Affairs, Pfizer, Seoul, South Korea., Song JY; Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, South Korea. |
| Jazyk: |
angličtina |
| Zdroj: |
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2024 Dec 31; Vol. 20 (1), pp. 2429235. Date of Electronic Publication: 2024 Dec 04. |
| DOI: |
10.1080/21645515.2024.2429235 |
| Abstrakt: |
This study aims to provide a comprehensive review of literature on pneumococcal disease burden in high-risk older adults aged ≥65 with focus on impact of comorbidities, long-term care facilities (LTCFs), antibiotic resistance, and vaccination policies across various countries. Research showed that the disease burden and the prevalence of antibiotic-resistant pneumococci was higher in the elderly, particularly those residing in LTCFs, and with comorbidities. These individuals are at high risk of infection with antibiotic-resistant serotypes 10A, 11A, and 15B. The vaccination strategies and national guidelines for pneumococcal vaccines in the elderly vary across countries. Some countries focus on single-dose strategies, while others recommend sequential vaccinations with varying intervals. Although vaccination policies are well-established for the elderly, they are not as well-established for high-risk elderly groups, and this review underscores the need for more tailored vaccination strategies for these groups. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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