Antiviral target compound profile for pandemic preparedness.

Autor: Demarest JF; INTREPID Alliance, Cambridge, MA, USA., Draghia-Akli R; INTREPID Alliance, Cambridge, MA, USA., Cihlar T; INTREPID Alliance, Cambridge, MA, USA.; Gilead Sciences, Foster City, CA, USA., Bradley K; INTREPID Alliance, Cambridge, MA, USA.; Roche pharmaceutical Research and Early Development (pRED), Basel, Switzerland., Young JAT; INTREPID Alliance, Cambridge, MA, USA.; Roche pharmaceutical Research and Early Development (pRED), Basel, Switzerland., Chandra R; Novartis Pharmaceuticals, East Hanover, NJ, USA., Vaidyanathan S; Novartis Pharmaceuticals, East Hanover, NJ, USA., Chu-Moyer M; Amgen, Thousand Oaks, CA, USA., Lynch CL; AbbVie, North Chicago, IL, USA., Campbell A; AbbVie, North Chicago, IL, USA., Saikatendu KS; Takeda, San Diego, CA, USA., Bilello JP; Gilead Sciences, Foster City, CA, USA., Murata Y; Gilead Sciences, Foster City, CA, USA., van Loock M; Janssen Pharmaceutica NV, a Johnson & Johnson company, Beerse, Belgium., Hurt AC; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Tellinghuisen T; Roche pharmaceutical Research and Early Development (pRED), Basel, Switzerland., Ruggiero L; INTREPID Alliance, Cambridge, MA, USA., Mackman R; INTREPID Alliance, Cambridge, MA, USA., Hill NM; INTREPID Alliance, Cambridge, MA, USA., Pottage JC Jr; INTREPID Alliance, Cambridge, MA, USA. john.pottagemd@gmail.com.
Jazyk: angličtina
Zdroj: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2024 Dec 02. Date of Electronic Publication: 2024 Dec 02.
DOI: 10.1038/s41573-024-01102-3
Abstrakt: Competing Interests: Competing interests: T.C., J.P.B., and Y.M. are employees of Gilead Sciences. K.B., J.A.T.Y., A.C.H., and T.T. are employees of F. Hoffmann-LaRoche. R.C. and S.V. are employees of Novartis Pharmaceuticals. C.L.L and A.C. are employees of AbbVie. M.v.L. is an employee of Janssen Pharmaceutica. J.F.D., R.D.-A., K.S.S., M.C.-M., L.R., R.M., N.M.H, and J.C.P. declare no competing interests.
Databáze: MEDLINE