Problematic Substance Use in Depressed Youth: Associations with Suicidal Ideation and Suicide Attempt History.

Autor:	Armstrong GM; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA., Anderberg JL; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA., Gorman AR; Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Spencer SD; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA., Minhajuddin A; Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ecker AH; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.; Houston VA HSR&D Center for Innovation in Quality, Michael E DeBakey VA Medical Center, Effectiveness and Safety, Houston, TX, USA.; South Central Metal Illness Research Education and Clinical Center (a Virtual Center), Houston, TX, USA.; Substance Disorders Treatment Program, Michael E DeBakey VA Medical Center, Houston, TX, USA., Spofford J; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.; Substance Disorders Treatment Program, Michael E DeBakey VA Medical Center, Houston, TX, USA., Guzick AG; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.; Department of Psychiatry and Behavioral Sciences, University of Pennsylvania, Philadelphia, PA, USA., Slater H; Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Aloor FZ; Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, TX, USA., Flores AM; Department of Psychiatry, University of Texas Health Science Center, San Antonio, TX, USA., Lagrone JM; Ascension Medical Group, Austin, TX, USA., Marino EN; Be Well Institute for Substance Use and Related Disorders, University of Texas Health Science Center, San Antonio, TX, USA., Soutullo CA; Louis A. Faillace MD Department of Psychiatry and Behavioral Sciences, University of Texas Health (UT Health), Houston, TX, USA., Wakefield SM; Department of Psychiatry, Texas Tech University Health Science Center, Lubbock, TX, USA., Goodman WK; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA., Trivedi MH; Center for Depression Research and Clinical Care, Peter O'Donnell Jr. Brain Institute and Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA., Storch EA; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
Jazyk:	angličtina
Zdroj:	Journal of dual diagnosis [J Dual Diagn] 2024 Dec 02, pp. 1-14. Date of Electronic Publication: 2024 Dec 02.
DOI:	10.1080/15504263.2024.2434219
Abstrakt:	Objective:  Depressed youth exhibit higher rates of suicidal behavior compared to healthy controls, with problematic substance use potentially intensifying this risk. Accordingly, this study aimed to examine the impact of comorbid depression and problematic substance use and its association with suicidality in youth populations. Methods:  We examined differences in clinical features and demographic characteristics between 797 depressed youth ages 8-20 years with and without problematic substance use from the Texas Youth Depression and Suicide Research Network (TX-YDSRN). Additionally, to assess whether the effect of depression severity on suicidal ideation and suicide attempt history were influenced by problematic substance use, multivariable linear and logistic regression analyses were conducted. Results:  Depressed youth with problematic substance use (versus those without) were significantly older, more likely to exhibit suicidal ideation and a history of suicide attempts and had significantly worse school functioning after controlling for age, sex, race, and ethnicity. Problematic substance use did not moderate the effect of depression severity on suicidal ideation or suicide attempt history. Conclusions:  Findings shed light on the impact of problematic substance use in depressed youth which may allow for earlier and more specified intervention efforts aimed at identifying and targeting youth suicidality.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu