Association between omega-3 index and depersonalization among healthcare workers in a university hospital: a cross-sectional study.

Autor:	Antao HS; Faculty of Medicine, University of Lisbon, Lisbon, Portugal., Sacadura-Leite E; Faculty of Medicine, University of Lisbon, Lisbon, Portugal.; Public Health Research Center (PHRC), National School of Public Heath, Lisbon, Portugal.; Occupational Health Department, Santa Maria Local Health Unit, Lisbon, Portugal.; Comprehensive Health Resource Center (CHRC), NOVA University of, Lisbon, Portugal., Aguiar P; Public Health Research Center (PHRC), National School of Public Heath, Lisbon, Portugal.; Comprehensive Health Resource Center (CHRC), NOVA University of, Lisbon, Portugal., Gois C; Faculty of Medicine, University of Lisbon, Lisbon, Portugal., Marques J; Biostatistics, Amadora/Sintra Local Health Unit, Amadora, Portugal., Pombo S; Psychology and Psychiatry Clinic, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.; Department of Psychiatry and Mental Health, Santa Maria Local Health Unit, Lisbon, Portugal., Figueira ML; Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
Jazyk:	angličtina
Zdroj:	Frontiers in psychiatry [Front Psychiatry] 2024 Nov 15; Vol. 15, pp. 1425792. Date of Electronic Publication: 2024 Nov 15 (Print Publication: 2024).
DOI:	10.3389/fpsyt.2024.1425792
Abstrakt:	Introduction: Burnout harms workers physical and mental health due to induced brain changes, autonomous nervous system and hypothalamus-pituitary-adrenal axis excessive activation. Although several correlations and risk factors have been identified, the research around burnout biological correlates remains underdeveloped. The omega-3 index has been proposed in mental health as a contributor to identify high risk patients and monitor disease advancements but the evidence on its relationship with burnout is limited. This study is meant to test the hypothesis that the omega-3 index is inversely associated with burnout levels and to discuss its potential as a biological correlate of burnout. Methods: It had an observational, cross-sectional design and was carried out at a university hospital center between March 2021 and July 2023. We invited 319 healthcare professionals (doctors and nurses) at the occupational health and emergency departments. The omega- 3 index was determined through a prick finger test. Emotional exhaustion, depersonalization and personal accomplishment were measured by the Maslach Burnout Inventory. Descriptive analyses were conducted to examine the participants' characteristics and outcome variables. Means, medians, interquartile ranges and standard deviations were calculated for continuous variables. Frequencies and percentages were obtained for categorical variables. We have used the individual dimensions' scores as continuous data in the evaluation of their relationship with the omega-3 index. The relationship between burnout levels and the omega-3 index was assessed through linear regression analysis. Results: We surveyed 300 subjects (94% response rate). High emotional exhaustion and depersonalization were reported by 29.9% and 22.1% of participants, respectively; 26.0% reported low personal accomplishment. The mean omega-3 index was 5.75%. The depersonalization score was, on average, 11.132 points higher (95% CI [4.661; 17.603]) in individuals whose omega-3 index was lower than 4%. Discussion: An omega-3 index below 4% seems to potentially be a biological correlate of depersonalization. Our results contribute to enlarging the knowledge about burnout biological correlates, an area that has been previously signalled as underdeveloped. Omega-3 index should be included in prospective studies that will investigate the evolution of other burnout biological correlates as the syndrome emerges and progresses in subjects at risk. Competing Interests: The author(s) declare financial support was received for the research, authorship, and/or publication of this article. The omega-3 index test kits used in this research and the APC were funded by the Portuguese subsidiary of Recordati Group, Jaba Recordati. The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article, or the decision to submit it for publication. (Copyright © 2024 Antao, Sacadura-Leite, Aguiar, Gois, Marques, Pombo and Figueira.)
Databáze:	MEDLINE
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