Italian validation of the IBD-disk tool for the assessment of disability in inflammatory bowel diseases: A cross-sectional multicenter study.

Autor: Nardone OM; Gastroenterology, Department of Public Health, University of Naples Federico II, Naples, Italy., Bruzzese D; Department of Public Health, University Federico II, Naples, Italy., Allocca M; Gastroenterology and Endoscopy Unit, IRCCS Hospital San Raffaele and University Vita-Salute San Raffaele, Milan, Italy., Calabrese G; Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples Federico  II, Naples, Italy., Caprioli F; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Gastroenterology and Endoscopy Unit, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico di Milano, Italy., Danese S; Gastroenterology and Endoscopy Unit, IRCCS Hospital San Raffaele and University Vita-Salute San Raffaele, Milan, Italy., Fantini MC; Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy., Onali S; Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy., Orlando A; IBD Unit, Department of Medicine, 'Villa Sofia-Cervello' Hospital, 90146 Palermo, Italy., Rispo A; Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples Federico  II, Naples, Italy., Savarino E; Gastroenterology Unit, Azienda Ospedale Università Padova, Padova, Italy; Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Soriano A; Internal Medicine Department, Gastroenterology Division and IBD Center, Azienda Unità Sanitaria Locale-IRCCS, Reggio Emilia, Italy., Testa A; Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples Federico  II, Naples, Italy., Variola A; IBD Unit, IRCCS Sacro Cuore Don Calabria, Negrar, Italy., Castiglione F; Gastroenterology, Department of Clinical Medicine and Surgery, University of Naples Federico  II, Naples, Italy. Electronic address: fabcasti@unina.it.
Jazyk: angličtina
Zdroj: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2024 Nov 30. Date of Electronic Publication: 2024 Nov 30.
DOI: 10.1016/j.dld.2024.11.004
Abstrakt: Introduction: IBD-Disk is a simple, easy-to-use, and self-administered analogue visual tool for assessing disability in patients with Inflammatory Bowel Disease (IBD). However, it has not yet been validated in Italian. This study aims to validate IBD-Disk in an Italian cross-sectional multicentre study.
Methods: This study was conducted in eight IBD centres from February 2023 to October 2023. After forward-backwards translation of IBD-Disk into Italian, patients consecutively completed IBD-Disk (at baseline and after 7 days), IBD-Disability Index (IBD-DI) and IBDQ-32 for quality of life.
Results: We enrolled 767 patients (377, 49,2% CD; 390, 50,8% UC) who completed the IBD-Disk [median score of 30 (IQR=11-52)]. Internal consistency was excellent, with Cronbach's α of 0.92 (95%CI=0.92-0.92). To evaluate the validity, the IBD-Disk was compared with the IBD-DI and IBDQ-32, revealing a significant positive correlation of 0.70 (95% CI=0.66-0.73; p<0.001) and 0.83 (r=0.83, 95% CI=0.80-0.85; p<0.001), respectively. The intraclass correlation coefficient (ICC) was 0.84 (95% CI=0.82-0.86) for test-retest. Female gender, clinically active IBD and the presence of extraintestinal manifestations led to higher IBD-Disk scores.
Conclusion: This study validated the IBD-Disk in a large cohort of Italian IBD patients, demonstrating that it is a valid, reliable and responsive tool for quantifying IBD-related disability. This validation facilitates its integration into the daily clinical management of IBD patients.
Competing Interests: Conflict of interest All authors declare no conflict of interest regarding this manuscript.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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