The Structural and Thermal properties of Badarashma Pishti.

Autor:	Jagtap CY; Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, 284003, India. Electronic address: drshikhar84@gmail.com., Charde V; Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, 284003, India., Rawat H; Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, 284003, India., Dane G; Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, 284003, India., Mishra AK; Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, 284003, India., Narasimhaji CV; Central Ayurveda Research Institute, Jhansi, Uttar Pradesh, 284003, India., Sharma BS; Central Council for Research in Ayurvedic Sciences, New Delhi, 110058, India., Khanduri S; Central Council for Research in Ayurvedic Sciences, New Delhi, 110058, India., Singh R; Central Council for Research in Ayurvedic Sciences, New Delhi, 110058, India., Srikanth N; Central Council for Research in Ayurvedic Sciences, New Delhi, 110058, India., Acharya R; Central Council for Research in Ayurvedic Sciences, New Delhi, 110058, India.
Jazyk:	angličtina
Zdroj:	Journal of Ayurveda and integrative medicine [J Ayurveda Integr Med] 2024 Nov 29; Vol. 15 (6), pp. 100989. Date of Electronic Publication: 2024 Nov 29.
DOI:	10.1016/j.jaim.2024.100989
Abstrakt:	Background: Lapis judaicus, or Jews stone (Badarashma), has been used in treating kidney and bladder stones since ancient times by Ayurvedic and Unani medicinal practitioners. A limited number of studies have been carried out using Ayurvedic preparations derived from gems or precious stones that were used traditionally. In Ayurveda, Rasa Shastra includes the fabrication of Bhasmas and Pishti. Objective: This study aimed to prepare and characterize Badarashma Pishti formulation (Lapis judaicus microparticles) and investigate its structural and thermal properties. Materials and Methods: The microparticles were prepared by subjecting purified powder of Lapis judaicus to a wet levigation (Bhavana) process. Characterizations were done using Fourier transform infrared spectroscopy (FTIR), Differential scanning calorimetry (DSC), thermo-gravimetry analysis (TGA), energy-dispersive X-ray (EDAX) spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM) analysis. Physicochemical characterization, elemental analysis, particle size distribution study, and identification of heavy metals were also performed. Results: A standard operating procedure was developed to formulate Badarashma Pishti. The obtained microparticles were irregularly shaped with a size of 4.290 ± 0.472 μm, confirmed in SEM images. The FTIR and XRD of prepared Badarashma Pishti samples revealed the presence of calcite, quartz, and aragonite minerals. The results of EDAX also confirmed the presence of Ca, Mg, O, and Si elements. Conclusion: The proposed study results reveal great insights for determining the authenticity, purity, and standardization parameters of inorganic mineral drugs, proving to be a useful delivery system for treating renal calculi. Competing Interests: Conflict of interest The authors announce that there are no competing interests. (Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu