Indoor bioaerosols and asthma: Overview, implications, and mitigation strategies.

Autor: Dannemiller KC; Civil, Environmental, and Geodetic Engineering, College of Engineering, The Ohio State University, Columbus, OH, USA; Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, OH, USA; Sustainability Institute, College of Engineering, The Ohio State University, Columbus, OH, USA. Electronic address: Dannemiller.70@osu.edu., Conrad LA; Department of Pediatrics, Albert Einstein College of Medicine, Bronx, New York, USA., Haines SR; Department of Civil & Mineral Engineering, Faculty of Applied Science & Engineering, University of Toronto, Toronto, Ontario, Canada., Huang YJ; Department of Medicine (Division of Pulmonary and Critical Care Medicine), University of Michigan, Ann Arbor, MI, USA; Department of Microbiology and Immunology, University of Michigan, Ann Arbor MI., Marr LC; Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA, USA., Siegel JA; Department of Civil & Mineral Engineering, Faculty of Applied Science & Engineering, University of Toronto, Toronto, Ontario, Canada., Hassan S; Department of Civil & Mineral Engineering, Faculty of Applied Science & Engineering, University of Toronto, Toronto, Ontario, Canada., King JC; Civil, Environmental, and Geodetic Engineering, College of Engineering, The Ohio State University, Columbus, OH, USA; Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, OH, USA; Environmental Science Graduate Program, The Ohio State University, Columbus, OH, USA., Prussin AJ 2nd; Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA, USA., Shamblin A; Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, OH, USA; Infectious Diseases Institute Genomic and Microbiology Solutions (IDI-GEMS), The Ohio State University, Columbus, OH, USA., Perzanowski MS; Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
Jazyk: angličtina
Zdroj: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2024 Nov 27. Date of Electronic Publication: 2024 Nov 27.
DOI: 10.1016/j.jaci.2024.11.027
Abstrakt: Aerosolized particles with a biological origin are called bioaerosols. Bioaerosols from plants, animals, fungi, bacteria and viruses are an important class of environmental exposures that are clinically relevant to asthma. However, there are important differences in the pathways by which various bioaerosols impact asthma. Additionally, differences in individual susceptibility to different bioaerosols impact exposure reduction and mitigation strategies. Strategies to reduce exposures to potential triggers of asthma are routinely considered as part of standard clinical care and asthma management guidelines. Ventilation standards in buildings may reduce bioaerosol exposure for everyone, but are not necessarily designed specifically to protect patients with asthma. Direct measurement of a bioaerosol is not generally necessary for practical applications where the relevant source of the bioaerosol has been identified. Different types of bioaerosols can be controlled with similar strategies that prioritize source control (e.g. reducing resuspension, integrated pest management, controlling moisture), and can be supplemented by enhancing air filtration. The goal of this review is to summarize the latest information on bioaerosols, including allergens, fungi, bacteria and viruses, that have been associated with adverse asthma outcomes and to discuss mitigation options.
(Copyright © 2024. Published by Elsevier Inc.)
Databáze: MEDLINE
Externí odkaz: