Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment.
Autor: | Sahoo AK; The Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, India., Madgaonkar SR; The Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, India., Chivukula N; The Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, India., Karthikeyan P; National Centre for Coastal Research, Ministry of Earth Sciences, Government of India, Pallikaranai, Chennai, India., Ramesh K; The Institute of Mathematical Sciences (IMSc), Chennai, India., Marigoudar SR; National Centre for Coastal Research, Ministry of Earth Sciences, Government of India, Pallikaranai, Chennai, India., Sharma KV; National Centre for Coastal Research, Ministry of Earth Sciences, Government of India, Pallikaranai, Chennai, India., Samal A; The Institute of Mathematical Sciences (IMSc), Chennai, India; Homi Bhabha National Institute (HBNI), Mumbai, India. Electronic address: asamal@imsc.res.in. |
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Jazyk: | angličtina |
Zdroj: | Environment international [Environ Int] 2024 Nov 24; Vol. 194, pp. 109163. Date of Electronic Publication: 2024 Nov 24. |
DOI: | 10.1016/j.envint.2024.109163 |
Abstrakt: | Petroleum hydrocarbons (PHs) are compounds composed mostly of carbon and hydrogen, originating from crude oil and its derivatives. PHs are primarily released into the environment through the diffusion of oils, resulting from anthropogenic activities like transportation and offshore drilling, and accidental incidents such as oil spills. Once released, these PHs can persist in different ecosystems and cause long-term detrimental ecological impacts. While the hazards associated with such PH contaminations are often assessed by the concentrations of total petroleum hydrocarbons in the environment, studies focusing on the risks associated with individual PHs are limited. In this study, different network-based frameworks were utilized to explore and understand the adverse ecological effects associated with PH exposure. First, a list of 320 PHs was systematically curated from published reports. Next, biological endpoint data from toxicological databases was systematically integrated, and a stressor-centric adverse outcome pathway (AOP) network, linking 75 PHs with 177 ecotoxicologically-relevant high confidence AOPs within AOP-Wiki, was constructed. Further, stressor-species networks, based on reported toxicity concentrations and bioconcentration factors data within ECOTOX, were constructed for 80 PHs and 28 PHs, respectively. It was found that crustaceans are documented to be affected by many of these PHs. Finally, the aquatic toxicity data within ECOTOX was used to construct species sensitivity distributions for PHs, and their corresponding hazard concentrations (HC05), that are harmful to 5% of species in the aquatic ecosystem, were derived. Further, the predicted no-effect concentrations (PNECs) and risk quotients for the US EPA priority polycyclic aromatic hydrocarbons (PAHs) were computed by using their environmental concentration data for Indian coastal and river waters. Overall, this study highlights the importance of using network-based approaches and risk assessment methods to understand the PH-induced toxicities effectively. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.) |
Databáze: | MEDLINE |
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