Draft genome of a human gut-derived Blautia sp. that ameliorates colitis and colitis-associated sociability deficits in mice.

Autor: Murphy MA; Department of Pathology, Division of Microbiology and Immunology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Brown DG; Department of Pathology, Division of Microbiology and Immunology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Bell RS; Department of Pathology, Division of Microbiology and Immunology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Weis AM; Department of Pathology, Division of Microbiology and Immunology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Barrios LA; Department of Pathology, Division of Microbiology and Immunology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Stephens WZ; Department of Pathology, Division of Microbiology and Immunology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA., Round JL; Department of Pathology, Division of Microbiology and Immunology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Jazyk: angličtina
Zdroj: Microbiology resource announcements [Microbiol Resour Announc] 2024 Nov 29, pp. e0072624. Date of Electronic Publication: 2024 Nov 29.
DOI: 10.1128/mra.00726-24
Abstrakt: Blautia is a genus of anaerobic, gram-positive bacteria commonly found in mammalian gastrointestinal tracts. Yet, how variations among different Blautia strains can impact host health is poorly understood. We present a Blautia sp. genome isolated from human feces whose supplementation to mice can ameliorate colitis severity and associated sociability deficits.
Databáze: MEDLINE