Gastrointestinal Bleeding/Angiodysplasia in Patients With Glanzmann Thrombasthenia.
| Autor: | Tarawah RA; Department of Medicine, King Fahad Hospital, Madinah, Saudi Arabia., Tarawah AM; Madinah Hereditary Blood Disorders Centre, Department of Hematology and Oncology, King Salman Bin Abdulaziz Medical City, Madinah, Saudi Arabia. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Journal of medical cases [J Med Cases] 2024 Dec; Vol. 15 (12), pp. 401-405. Date of Electronic Publication: 2024 Nov 11. |
| DOI: | 10.14740/jmc4340 |
| Abstrakt: | Glanzmann thrombasthenia (GT) is a common type of bleeding disorder, with a prevalence of 1/10,000 in Al Madinah, Saudi Arabia. GT causes bleeding owing to the lack of platelet aggregation associated with glycoprotein IIb/IIIa deficiency, which is characterized by mucocutaneous bleeding symptoms, such as epistaxis, gingival bleeding, and menorrhagia. Gastrointestinal angiodysplasia (GIAD) is a rare presentation of GT, where eight cases have been reported. GIAD is a vascular malformation of the digestive system caused by abnormal angiogenesis. Treatment of GIAD include surgical resection, electrocoagulation, embolization, and medical therapy with octreotide, thalidomide, and bevacizumab. GIAD has a high tendency to recur. We report the cases of eight patients of different ages who were diagnosed with GT and presented with gastrointestinal bleeding. Competing Interests: None to declare. (Copyright 2024, Tarawah et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|