Optic neuropathy as an initial manifestation of acute retinal necrosis caused by varicella zoster virus: a case report.

Autor: Li L; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China., Wu Q; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China., Tian Q; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China., Han G; Shandong Academy of Eye Disease Prevention and Therapy, Jinan, Shandong, 250002, China., Xie X; Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250002, China. yankeboshi@126.com.
Jazyk: angličtina
Zdroj: BMC ophthalmology [BMC Ophthalmol] 2024 Nov 27; Vol. 24 (1), pp. 512. Date of Electronic Publication: 2024 Nov 27.
DOI: 10.1186/s12886-024-03783-1
Abstrakt: Background: We present the treatment and follow-up of a rare patient with acute retinal necrosis (ARN) with optic neuropathy as the first manifestation.
Case Presentation: A 57-year-old male patient first presented with reduced vision and optic neuropathy in his right eye.After 20 days, the vision in the left eye decreased, and the slit-lamp examination showed no remarkable changes in the anterior segment. The right eye showed 2 + cells and flares in the anterior chamber. The iris texture was good, the pupils were round (light reflex), the crystalline lens was slightly opaque, and the vitreous was turbid. An anterior chamber paracentesis was performed to collect aqueous humor for polymerase chain reaction testing. The PCR test showed positive detection of VZV in the right eye, while the content of VZV in the left eye was lower than the reference value. Both eyes of the patient were successively diagnosed with acute retinal necrosis (ARN) due to VZV infection. The patient was treated with topical antiviral and anti-inflammatory eye medication, oral steroids, and general antiviral drugs. After three months, the vision and condition were relatively stable.
Conclusions: Clinicians should realize that accurate diagnosis and timely antiviral therapy are crucial for treating ARN.
Competing Interests: Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Written informed consent was obtained from the patient for the publication of this case report. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s).)
Databáze: MEDLINE
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