Congenital intracranial immature teratoma in a preterm infant: illustrative case.

Autor: Saleem A; Neurosurgery Department, Ibn Sina Hospital, Kuwait City, Kuwait. atharysaleem@gmail.com.; Kuwait Institution of Medical Specialization (KIMS), Kuwait City, Kuwait. atharysaleem@gmail.com., Alqallaf A; Neurosurgery Department, Ibn Sina Hospital, Kuwait City, Kuwait.; Kuwait Institution of Medical Specialization (KIMS), Kuwait City, Kuwait., Alduwailah M; Neurosurgery Department, Ibn Sina Hospital, Kuwait City, Kuwait., Zulfiqar N; Neurosurgery Department, Ibn Sina Hospital, Kuwait City, Kuwait., Saleh S; Ophthalmology Department, Adan Hospital, Al Ahmadi, Kuwait., Alrabea A; Ophthalmology Department, Adan Hospital, Al Ahmadi, Kuwait., Mijalcic R; Neurosurgery Department, Ibn Sina Hospital, Kuwait City, Kuwait., Alsheikh T; Neurosurgery Department, Ibn Sina Hospital, Kuwait City, Kuwait.; Kuwait Institution of Medical Specialization (KIMS), Kuwait City, Kuwait.
Jazyk: angličtina
Zdroj: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery [Childs Nerv Syst] 2024 Nov 27; Vol. 41 (1), pp. 4. Date of Electronic Publication: 2024 Nov 27.
DOI: 10.1007/s00381-024-06666-4
Abstrakt: Background: Congenital intracranial immature teratoma is a rare tumor that is present in the first year of life. It is composed of three embryonic germ layers. These tumors are mainly manifested by hydrocephalus. Radiological investigations and histopathological studies are crucial to evaluating and diagnosing intracranial immature teratoma. Few cases were documented in the literature.
Observations: In this case, we highlight a preterm infant born with grade III proptosis and an intracranial space-occupying lesion that was diagnosed as high-grade congenital intracranial immature teratoma by brain MRI and histopathology studies. Neoadjuvant chemotherapy was used after the failure of the initial first attempt of craniotomy and lesion resection. Although, the tumor size increased post-chemotherapy, both intracranial and orbital parts of the lesion were excised efficiently with minimal blood loss, achieving complete tumor resection.
Lessons: We demonstrate a case of a rare congenital brain tumor in the pediatric population. We report the diagnostic and treatment challenges besides the effective intraoperative role of neoadjuvant chemotherapeutic agents. To our knowledge, the current case is one of the few published cases of intracranial immature teratoma that presented with ophthalmic manifestations.
Competing Interests: Declarations. Conflict of interest: The authors declare no competing interests. Open access: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third-party material in this article are included in the article’s Creative Commons license unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ .
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE
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