Using RET-He and Delta-He in the Sysmex XN-1000V Analyzer to Differentiate Between Chronic Hemorrhagic and Chronic Inflammatory Anemia in Small Animals.

Autor: Perez-Ecija A; Department of Animal Medicine and Surgery, Campus Rabanales, University of Cordoba, Road Madrid-Cadiz km 396, 14104 Cordoba, Spain.; Veterinary Teaching Hospital, Campus Rabanales, University of Cordoba, Road Madrid-Cadiz km 396, 14104 Cordoba, Spain., Fernandez-Castañer J; Veterinary Teaching Hospital, Campus Rabanales, University of Cordoba, Road Madrid-Cadiz km 396, 14104 Cordoba, Spain., Martinez C; Department of Animal Medicine and Surgery, Campus Rabanales, University of Cordoba, Road Madrid-Cadiz km 396, 14104 Cordoba, Spain.; Veterinary Teaching Hospital, Campus Rabanales, University of Cordoba, Road Madrid-Cadiz km 396, 14104 Cordoba, Spain., Mendoza FJ; Department of Animal Medicine and Surgery, Campus Rabanales, University of Cordoba, Road Madrid-Cadiz km 396, 14104 Cordoba, Spain.; Veterinary Teaching Hospital, Campus Rabanales, University of Cordoba, Road Madrid-Cadiz km 396, 14104 Cordoba, Spain.
Jazyk: angličtina
Zdroj: Animals : an open access journal from MDPI [Animals (Basel)] 2024 Nov 09; Vol. 14 (22). Date of Electronic Publication: 2024 Nov 09.
DOI: 10.3390/ani14223215
Abstrakt: Chronic hemorrhagic anemia (CHA) and anemia of chronic inflammation (ACI) are difficult to differentiate in small animals using hematology. Advanced hematological parameters (RET-He, Delta-He and %Hypo-He) are used in humans to discriminate between types of non-regenerative anemia. Whether they could be useful in the diagnosis of CHA and ACI in small animals is unknown. We evaluated these parameters in the Sysmex XN-1000V analyzer in a population of non-anemic and anemic dogs and cats. Delta-He was significantly different between dogs with CHA and ACI. Moreover, Delta-He and RET-He were different between healthy and non-anemic dogs with inflammation. Neither of these two statements was true for cats. We also report the reference ranges for these parameters using the Sysmex XN-1000V. Although additional clinical and laboratory information should always be considered, the measurement of these parameters using this analyzer can help clinicians to classify type of anemia.
Databáze: MEDLINE
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