Invasive Pneumococcal Diseases in People over 65 in Veneto Region Surveillance.

Autor:	Cocchio S; Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.; Preventive Medicine and Risk Assessment Unit, Azienda Ospedale Università Padova, 35128 Padua, Italy., Cozzolino C; Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy., Cozza A; Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy., Furlan P; Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy., Amoruso I; Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy., Zanella F; Regional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy., Da Re F; Regional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy., Ballarin D; Regional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy., Pagin G; Regional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy., Gentili D; Regional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy., Tonon M; Regional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy., Russo F; Regional Directorate of Prevention, Food Safety, Veterinary, Public Health-Veneto Region, 30123 Venice, Italy., Baldovin T; Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy., Baldo V; Department of Cardiac, Thoracic, Vascular Sciences, and Public Health, University of Padua, 35128 Padua, Italy.; Preventive Medicine and Risk Assessment Unit, Azienda Ospedale Università Padova, 35128 Padua, Italy.
Jazyk:	angličtina
Zdroj:	Vaccines [Vaccines (Basel)] 2024 Oct 23; Vol. 12 (11). Date of Electronic Publication: 2024 Oct 23.
DOI:	10.3390/vaccines12111202
Abstrakt:	Background: Elderly individuals over 65, along with children under 5, are the most affected by invasive pneumococcal diseases (IPDs). Monitoring vaccination coverage and conducting surveillance are essential for guiding evidence-based prevention campaigns and public health measures. Methods: Since 2007, the Veneto Region has relied on three sources for surveillance of invasive bacterial infections, contributing to an increase in reported IPD cases. This study analyzed notifications related to individuals aged ≥65 years from 2007 to 2023. Results: A total of 1527 cases of IPDs in elderly individuals were reported between 2007 and 2023. The notification rate significantly increased from 5.61 to 14.63 per 100,000 inhabitants, despite underreporting during the COVID-19 pandemic. Cases associated with sepsis increased from 3.89 to 9.58 per 100,000, while notifications of meningitis and case fatality rates remained stable at 1.5 per 100,000 and 11.8%, respectively. Serotyping was not performed in 52% of the notifications. The most common serotypes were 3 (21.6%), 8 (11.1%), and 19A (5.0%), with fluctuations over time. There was a significant decline in serotypes covered by PCV7 and PCV13 and an increase in non-vaccine serotypes. Conclusions: The regional surveillance system allows for an increasingly comprehensive profile of the epidemiological landscape of IPDs in Veneto. However, the surveillance of pneumococcal infections still presents challenges. The currently available data are likely to be underestimated, mainly referring to the most severe cases, and the serotyping necessary to identify the etiological agent is still not often performed.
Databáze:	MEDLINE
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