Imaging Assessment of Prostate Cancer Extra-Prostatic Extension: from histology to controversies.

Autor: Torres CVS; Radiologist, Post-graduation Scholar - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Gouvea GL; Radiologist, Post-graduation Scholar - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Secaf AF; Radiologist, Post-graduation Scholar - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Vieira DFM; Radiologist, Post-graduation Scholar - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Morgado ASM; Radiologist, Post-graduation Scholar - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Palma MM; Radiologist, Post-graduation Scholar - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Ramos GA; Radiologist, Post-graduation Scholar - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Elias J Jr; Full Professor - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil., Muglia VF; Associate Professor - Department of Imaging, Oncology and Hematology - Ribeirao Preto School of Medicine - University of Sao Paulo - Brazil. Electronic address: fmuglia@fmrp.usp.br.
Jazyk: angličtina
Zdroj: Seminars in ultrasound, CT, and MR [Semin Ultrasound CT MR] 2024 Nov 23. Date of Electronic Publication: 2024 Nov 23.
DOI: 10.1053/j.sult.2024.11.003
Abstrakt: Prostate cancer (PCa) is the most common non-skin malignancy among men and the fourth leading cause of cancer-related deaths globally. Accurate staging of PCa, particularly the assessment of extra-prostatic extension (EPE), is critical for prognosis and treatment planning. EPE, typically evaluated using magnetic resonance imaging (MRI), is associated with higher risks of positive surgical margins, biochemical recurrence, metastasis, and reduced overall survival. Despite the widespread use of MRI, there is no consensus on diagnosing EPE via imaging. There are two main scores assessing EPE by MRI: the European Society of Urogenital Radiology (ESUR) score and an MRI-based EPE grading system from an American group. While both are widely recognized, their differences can lead to varying interpretations in specific cases. This paper clarifies the anatomical considerations in diagnosing locally advanced PCa, explores EPE's impact on treatment and prognosis, and evaluates the relevance of MRI findings according to different criteria. Accurate EPE diagnosis remains challenging due to MRI limitations and inconsistencies in interpretation. Understanding these variations is crucial for optimal patient management.
Competing Interests: Declaration of Competing Interest All authors declare have no disclosures.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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