The relationship between systemic inflammation response index and clinical and histopathological features in gastric cancer.

Autor:	Pehlevan-Özel H; Department of Surgery, Mamak State Hospital, Ankara, Turkey., Dinç T; Department of General Surgery, School of Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Turkey., Okay ND; Department of Surgery, General Surgery Clinic, Ankara City Hospital, Ankara, Turkey., Tez M; Department of General Surgery, School of Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.
Jazyk:	angličtina
Zdroj:	Cirugia y cirujanos [Cir Cir] 2024 Nov 25. Date of Electronic Publication: 2024 Nov 25.
DOI:	10.24875/CIRU.23000234
Abstrakt:	Objective: The systemic inflammation response index (SIRI) is a marker used to predict survival. The aim of this study is to examine the relationship between SIRI and clinicopathological features and survival. Method: The relationship between clinicopathological characteristics and survey and SIRI was retrospectively investigated. Results: A total of 178 patients were included in the study. Poor prognostic factors such as tumor size, t, T-stage, tumor-node-metastasis (TNM) stage, and CA19-9 level were found to have a statistically significant relationship with patients with high SIRI (p = 0.039, p = 0.001, p = 0.001 and p = 0.013, respectively). A high SIRI was found to be an independent and poor prognostic factor for 3-year and 5-year survival (p = 0.014 and p = 0.027, respectively). Conclusions: High SIRI was associated with a poor survival rate, as were advanced TNM stage, advanced T stage, larger tumor size, and elevated CA19-9 level; all these are poor prognostic markers for gastric cancer.
Databáze:	MEDLINE
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