[Reproductive Risk Factors For Breast Cancer: A Case-Control Study].

Autor: Kané MB; Centre Hospitalier Universitaire Gabriel Touré, service de gynécologie - obstétrique, Bamako, Mali., Téguété I; Centre Hospitalier Universitaire Gabriel Touré, service de gynécologie - obstétrique, Bamako, Mali., Tounkara FK; Research Chair in Emergency Medicine Université Laval-CHAU Hôtel-Dieu de Lévis, Lévis, QC, Canada., Fané S; Centre Hospitalier Universitaire Gabriel Touré, service de gynécologie - obstétrique, Bamako, Mali., Djiré M; Centre Hospitalier Mère-enfant - Le Luxembourg, service de gynécologie - obstétrique, Bamako, Mali., Sidibé FM; Centre Hospitalier Universitaire du Point «G», service d'oncologie médicale et d'hématologie, Bamako, Mali., Traoré Y; Centre Hospitalier Universitaire Gabriel Touré, service de gynécologie - obstétrique, Bamako, Mali., Togo A; Centre Hospitalier Universitaire du Point «G», service d'oncologie médicale et d'hématologie, Bamako, Mali.; Centre Hospitalier Universitaire Gabriel Touré, service de chirurgie générale, Bamako, Mali.
Jazyk: francouzština
Zdroj: Le Mali medical [Mali Med] 2024; Vol. 39 (2), pp. 1-6.
Abstrakt: Breast cancer is the leading cancer in Mali. The objective of this study was to evaluate the risk factors of breast cancer associated with reproduction.
Patients and Methods: We conducted a case-control study (January 2017 - September 2021) at the Gabriel Touré Teaching Hospital. The sample consisted of 200 cases and 400 controls. A multivariable logistic regression model was used to identify reproductive factors associated with breast cancer. Adjusted odds ratios (AOR) were produced with their 95% confidence intervals.
Results: The mean age of cases was 46.1 years ± 14.6 vs 33.1 years ± 12.1 for controls. Menopausal women constituted 37.5 % of cases vs only 4% in the controls group. Nulliparity and breastfeeding were negatively associated with breast cancer (p <0,001) while postmenopausal women had a8.09-fold increase in the risk of breast cancer.
Conclusion: Nulliparity, breastfeeding and menopause were the reproductive factors associated with breast cancer in Mali.
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Databáze: MEDLINE
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