Not Just an Oxymoron: The Utilitarian's Guide to Antimicrobial Stewardship in Transplant Infectious Diseases.

Autor: Gorsline CA; University of Kansas Medical Center, Kansas City, Kansas, USA., Sharma D; Division of Infectious Diseases, Medical College of Georgia, Augusta, Georgia, USA., Harris CE; Division of Infectious Diseases, Medical University of South Carolina, Charleston, South Carolina, USA., Hand J; Division of Infectious Diseases, Ochsner Health, New Orleans, Louisiana, USA., Imlay H; Division of Infectious Diseases, University of Utah, Salt Lake City, Utah, USA., Stohs EJ; Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., So M; Leslie Dan Faculty of Pharmacy, University Health Network, University of Toronto, Toronto, Ontario, Canada., Kumar RN; Division of Infectious Disease and Tropical Medicine, MedStar Georgetown University Hospital, Washington, District of Columbia, USA.
Jazyk: angličtina
Zdroj: Transplant infectious disease : an official journal of the Transplantation Society [Transpl Infect Dis] 2024 Nov 25, pp. e14399. Date of Electronic Publication: 2024 Nov 25.
DOI: 10.1111/tid.14399
Abstrakt: Solid organ transplant and hematopoietic cell transplant patients face an increased risk of infectious diseases, greater exposure to antibiotics, and heightened risk of multidrug-resistant organisms (MDROs) due to their immunosuppressed state. Antimicrobial stewardship programs (ASP) are essential in reducing the incidence of MDRO by conserving antimicrobial use, minimizing treatment durations, and improving the appropriate use of diagnostic testing. However, the role of ASP in transplant infectious diseases (TID) is still evolving, necessitating greater collaboration between ASP and transplant programs. This collaboration will mitigate infection risks, reduce infection-associated costs, and improve outcomes. This article reviews the key components for implementing ASP in TID, especially for those that are establishing or growing their ASP to include TID, including specific goals, structure and funding, ASP initiatives (including antibiotic allergy delabeling, diagnostic stewardship, and antiviral/antifungal stewardship), metrics, and educational opportunities.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
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