Visit-to-visit variability of blood pressure and risk of diabetic retinopathy: a systematic review and meta-analysis.

Autor:	Noroozi M; Department of Biomedical Engineering, Faculty of Engineering, University of Isfahan Isfahan, Iran., Ghasemirad H; Student Research Committee, Shahid Sadoughi University of Medical Sciences Yazd, Iran., Ghaedi A; Student Research Committee, School of Medicine, Shiraz University of Medical Sciences Shiraz, Iran., Kargar M; Student Research Committee, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences Kerman, Iran., Alipour M; Medical Student, Department of Medicine, Islamic Azad University Tehran Medical Sciences Tehran, Iran., Mahmoudvand G; USERN Office, Lorestan University of Medical Sciences Khorramabad, Iran., Yaghoobpoor S; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences Tehran, Iran., Taherinik R; Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences Tehran, Iran., Erabi G; Student Research Committee, Urmia University of Medical Sciences Urmia, Iran., Amiri H; Student Research Committee, Arak University of Medical Sciences Arak, Iran., Keylani K; School of Pharmacy, Shahid Beheshti University of Medical Sciences Tehran, Iran., Mazhari SA; Student Research Committee, Azerbaijan Medical University Baku, Azerbaijan., Chichagi F; Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences Tehran, Iran., Dadkhah PA; Student Research Committee, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran., Mohagheghi SZ; School of Medicine, Iran University of Medical Sciences Tehran, Iran., Ansari A; Universal Scientific Education and Research Network (USERN) Tehran, Iran., Sheikh Z; Student Research Committee, School of Medicine, Babol University of Medical Sciences Babol, Iran., Deravi N; Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences Tehran, Iran.
Jazyk:	angličtina
Zdroj:	American journal of cardiovascular disease [Am J Cardiovasc Dis] 2024 Oct 15; Vol. 14 (5), pp. 281-294. Date of Electronic Publication: 2024 Oct 15 (Print Publication: 2024).
DOI:	10.62347/DFSZ9202
Abstrakt:	Background: Diabetes mellitus (DM), a worldwide disease affecting more than 400 million people, is associated with high blood pressure (BP). In addition to macrovascular complications, high BP in DM patients is potentially linked to microvascular complications. More than 70% of DM patients have retinopathy. To our knowledge, no systematic review and meta-analysis has been conducted on the relationship between visit-to-visit variability in blood pressure and diabetic retinopathy risk. Methods: This systematic review and meta-analysis study was performed on the related articles. The search strategy, screening, and data selection were all checklist-based. A comprehensive search was done in three databases, including PubMed, Google Scholar, and Scopus. The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) were followed. English clinical studies published up to January 2023 contained diabetic patients as the population, retinopathy as the outcome, and visit-to-visit blood pressure as the intervention. Using the QUIPS technique, two authors independently quantify the risk of bias in included publications. The meta-analysis was conducted using R version 4.4.1. We calculated relative risk (RR) as the effect size, applying the random effect model. Standard deviation (SD) and coefficient of variation (CV), were used as measures of BP variability. Results: A total number of 8 studies with 743,315 participants were covered in this systematic review. After meta-analysis, we concluded that the group with higher SD of BP variability had 2 percent higher risk than the control group (RR = 1.02, 95% CI = 1.01-1.03, I-squared = 41%); however, results of our analysis for CV of BP variability showed no significant contrast with control group thus no increased risk was reported (RR = 1.04, 95% CI = 0.94-1.15, I-squared = 32%, P -value = 0.23). Conclusion: In conclusion, an increased SD of BP variability significantly increased the relative risk for the development of retinopathy. Competing Interests: None. (AJCD Copyright © 2024.)
Databáze:	MEDLINE
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