Assessment of Construct Validity and Reliability of the Hospital Anxiety and Depression Scale in Greek Couples With Infertility Undergoing In Vitro Fertilization Cycles.

Autor:	Moutzouri M; Department of Midwifery, Faculty of Health and Care Sciences, University of West Attica, Athens, GRC., Koulierakis G; Department of Public Health Policy, Laboratory of Epidemiology, Health Determinants and Well-Being, Division of Epidemiology, Prevention and Quality of Life, University of West Attica, Athens, GRC., Sarantaki A; Department of Midwifery, Faculty of Health and Care Sciences, University of West Attica, Athens, GRC., Gourounti K; Department of Midwifery, Faculty of Health and Care Sciences, University of West Attica, Athens, GRC.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Oct 25; Vol. 16 (10), pp. e72350. Date of Electronic Publication: 2024 Oct 25 (Print Publication: 2024).
DOI:	10.7759/cureus.72350
Abstrakt:	Introduction: The Hospital Anxiety and Depression Scale (HADS) is a widely used screening instrument created to assess anxiety and depression symptoms during the experience of various health problems. It has also been increasingly applied to populations facing infertility. The current cross-sectional study aimed to assess the construct validity and reliability of the HADS in a sample of Greek participants undergoing in vitro fertilization (IVF) cycles. Materials and Methods: This study included 90 couples with infertility referred to an assisted reproduction unit in Heraklion, Greece, and an infertility center in Athens, Greece. To validate the scale, confirmatory factor analyses (CFA) were performed. Several goodness-of-fit indices were utilized including the comparative fit index (CFI), the root mean squared error of approximation (RMSEA), the standardized root mean square residual (SRMR), and normed chi-square index with the degree of freedom (c 2 /df). The reliability analysis was conducted by calculating Cronbach's alpha. Results: The confirmatory factor analysis revealed that all of the four fitness indexes were good (x 2 /df=1.489, CFI=0.943, RMSEA=0.052, SRMR=0.055). Based on the item-scale correlation coefficients, reliability was very good for the anxiety factor (alpha = 0.808), good for the depression factor (alpha = 0.707), and very good for the total questionnaire (alpha = 0.858). Conclusion: The results of confirmatory factor analyses and reliability analyses proved that HADS met the criteria of construct validity and reliability, making it suitable for use with couples undergoing an IVF cycle. Examining negative emotions, such as anxiety and depression, during the period of fertility problems and its treatment is important to evaluate the psychological maladjustment of couples with infertility and to create psychological interventions by health professionals that help individuals with infertility manage distress during IVF. Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Ethics Committee of University General Hospital of Heraklion (PAGNI) and Ethics Committee of Elena Venizelou Hospital issued approval 4342/10-4-2013 and 19229/22-9-2022, respectively. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: The publication of this study received funding from the "Special Account for Research Grants" (ELKE) of the University of West Attica, Athens, Greece. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Moutzouri et al.)
Databáze:	MEDLINE
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