Bioactive peptides derived from insect proteins: Preparation, biological activities, potential applications, and safety issues.

Autor: Tarahi M; Department of Food Science and Technology, School of Agriculture, Shiraz University, Shiraz, Iran., Aghababaei F; Aora Health, Calle Via de los Poblados, 17, 28033, Madrid, Spain., McClements DJ; Department of Food Science, University of Massachusetts, Amherst, MA 01003, United States., Pignitter M; Institute of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria., Hadidi M; Institute of Physiological Chemistry, Faculty of Chemistry, University of Vienna, Vienna 1090, Austria. Electronic address: milad.hadidi@gmail.com.
Jazyk: angličtina
Zdroj: Food chemistry [Food Chem] 2025 Feb 15; Vol. 465 (Pt 1), pp. 142113. Date of Electronic Publication: 2024 Nov 19.
DOI: 10.1016/j.foodchem.2024.142113
Abstrakt: Bioactive peptides are polypeptides with specific amino acid sequences that exhibit biological activities and health benefits. Insects have emerged as a sustainable source of proteins in human food and animal feed due to their efficient resource utilization, low environmental footprint, and good nutritional profile. Moreover, insect-derived bioactive peptides (IBPs) offer potential applications in functional foods and pharmaceuticals due to their antioxidant, antimicrobial, antihypertensive, anti-inflammatory, antidiabetic, and anti-obesity activities. In this article, the isolation, purification, and properties of IBPs are reviewed, as well as their potential health benefits, commercial applications, and safety. Despite the growing interest in incorporating IBPs into food products, challenges regarding consumer acceptance, safety, and regulations still persist. Thus, there is a pressing need for further research in this area, as well as clarification of the regulatory framework, before the full potential of insects as a sustainable source of bioactive peptides for human consumption can be realized.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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