EFFECTIVENESS OF ZERO SURGICAL INFECTION PROJECT (ZSIP) IN SPANISH HOSPITALS 2017-2021. A PROSPECTIVE COHORT STUDY.

Autor: Navarro-Gracia JF; Preventive Medicine Service. University General Hospital of Elche. Elche Spain. Electronic address: navarro_juagra@gva.es., Gómez-Romero FJ; Translational Research Unit. University General Hospital of Ciudad Real, Servicio de Salud de Castilla-La Mancha (SESCAM); Faculty of Medicine, Institute of Biomedicine (IB). Ciudad Real Spain. Electronic address: fjgomezr@sescam.jccm.es., Lozano-García FJ; Preventive Medicine Service. Burgos University Hospital Complex. Burgos Spain. Electronic address: jlozanoga@saludcastillayleon.es., Ortí-Lucas R; Preventive Medicine Service. University General Hospital of Valencia. Valencia Spain. Electronic address: orti_raf@gva.es., Delgado-De Los Reyes JA; Preventive Medicine Service. University Hospital of Vinalopó. Elche Spain. Electronic address: jadelgado@vinaloposalud.com., Fernández-Prada M; Preventive Medicine Service. Alvarez Buylla Hospital of Mieres. Mieres. Asturias Spain. Electronic address: mariafdezprada@gmail.com., Herruzo-Cabrera R; Chair of Preventive Medicine and Public Health. Autonomous University of Madrid. Madrid Spain. Electronic address: rafael.herruzo@uam.es.
Jazyk: angličtina
Zdroj: The Journal of hospital infection [J Hosp Infect] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.
DOI: 10.1016/j.jhin.2024.11.011
Abstrakt: Background: The Zero Surgical Infection Project (ZSIP) in Spain is a nation-wide program to prevent surgical site infections (SSI), sponsored by the Ministry of Health. The program includes the application of 5 key preventive measures (PM) grouped in a bundle: Perioperative antibiotic prophylaxis (PAP), skin antisepsis (SA), hair removal (HR), normothermia (NT) and normoglycemia (NG).
Aim: To assess the effectiveness of the bundle of 5 ZSIP preventive measures, applied in a set of Spanish public hospitals over the period 2017-2021, under standard conditions of surgical healthcare in Spain.
Methods: This was a prospective cohort study of 33,240 patients from the ZSIP Registry (National Database Network). It includes surveillance of SSI data of selected surgical interventions, compliance data and other risk factors. Compliance with the PM was verified through a specific checklist. The intervention and comparison groups were, those patients compliant and those non-compliant with the 5PM bundle, respectively. We calculated adjusted odds ratio (OR) and preventive fraction (PF) using logistic regression.
Findings: Overall SSI rate for patients in the compliant vs. not compliant 5PM bundle groups were 4.77% vs. 6.90%. Overall compliance of 5 PM bundle was 35.9%, and was higher in PAP (87.2%), SA (82.2%) and HR (78.7%). Compliance of 5PM bundle of ZSIP presents a PF of 32%, adjusted OR 0.68 (IC 95% 0.60-0.76).
Conclusion: The preventive intervention of the ZSIP implemented over the period 2017-21 in Spain achieved a significant level of effectiveness against SSI.
Competing Interests: Declaration of Competing Interest None.
(Copyright © 2024. Published by Elsevier Ltd.)
Databáze: MEDLINE
Externí odkaz: