Evaluation of hydrogen peroxide diffusion in the pulp chamber, bleaching efficacy, and physicochemical properties of an experimental in-office bleaching gel containing a hydroxyapatite-capsaicin composite.

Autor: Silva KL; Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, Bloco M, Uvaranas, Paraná, 4748, Brazil., Hortkoff D; Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, Bloco M, Uvaranas, Paraná, 4748, Brazil., Gorte G; Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, Bloco M, Uvaranas, Paraná, 4748, Brazil., Gumy F; Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, Bloco M, Uvaranas, Paraná, 4748, Brazil., Favoreto MW; Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, Bloco M, Uvaranas, Paraná, 4748, Brazil., Loguercio AD; Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, Bloco M, Uvaranas, Paraná, 4748, Brazil. aloguercio@hotmail.com., Farago PV; Department of Pharmaceutical Sciences, School of Pharmacy, State University of Ponta Grossa, Uvaranas, PR, Brazil.
Jazyk: angličtina
Zdroj: Odontology [Odontology] 2024 Nov 22. Date of Electronic Publication: 2024 Nov 22.
DOI: 10.1007/s10266-024-01022-z
Abstrakt: This study assessed the hydrogen peroxide (HP) diffusion into the pulp chamber, bleaching efficacy (BE), surface roughness (Ra), and Knoop microhardness (KHN) of an experimental bleaching gel containing a hydroxyapatite-capsaicin composite (HAp-CAP). Human premolars were randomly assigned to three groups (n = 9) based on the dental bleaching gel used (50 min; one session): only 35% HP, 35% HP + HAp-CAP, and not exposed to bleaching (negative control; NC). HP diffusion (µg/mL) into the pulp chamber was assessed using UV-Vis spectrophotometry, and BE (ΔE ab , ΔE 00 , and WI D ) was evaluated using a digital spectrophotometer. Human molars were used to determine Ra and KHN before and 7 days after the bleaching procedure, and for Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Spectroscopy (EDS) analyses. A paired t-test or t-test was used for statistical analysis (α = 0.05). A higher amount of HP into the pulp chamber and significant BE (ΔE ab , ΔE 00 , and WI D ) were observed for 35% HP and 35% HP + HAp-CAP compared to NC (p < 0.001), with no significant difference between them (p > 0.05). SEM and EDS demonstrated material deposition on the enamel surface after bleaching for 35% HP + HAp-CAP, which helped maintain the KHN (p > 0.05). Furthermore, Ra increased for both groups (p < 0.05). The 35% HP + HAp-CAP did not decrease HP diffusion into the pulp chamber, reduced KHN values, and increased Ra. Material deposition on the enamel surface was observed, and BE was effective.
Competing Interests: Declarations. Conflict of interest: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Karine Letícia da Silva declares that she has no conflict of interest. Diego Hortkoff declares that he has no conflict of interest. Gabriele Gorte declares that she has no conflict of interest. Fernanda Novak Gummy declares that she has no conflict of interest. Michael Willian Favoreto declares that he has no conflict of interest. Alessandro D. Loguercio declares that he has no conflict of interest. Paulo Vitor Farago declares that he has no conflict of interest. Ethical approval: This investigation was approved (protocol 5.435.477) by the scientific review committee and by the committee for the protection of human participants of the State University of Ponta Grossa, PR, Brazil. Informed consent: The informed consent does not apply in this study.
(© 2024. The Author(s), under exclusive licence to The Society of The Nippon Dental University.)
Databáze: MEDLINE
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