Mesenchymal stem cells and mesenchymal stem cell-derived exosomes: attractive therapeutic approaches for female reproductive dysfunction.

Autor: Hassanpour Khodaei S; Department of Dentistry, Eastern Mediterranean University (EMU) Famagusta, North Cyprus Mersin 10, Famagusta, Turkey., Sabetkam S; Department of Anatomy, Faculty of Medicine, University of Kyrenia, Kyrenia, Northern Cyprus., Kalarestaghi H; Research Laboratory for Embryology and Stem Cell, Department of Anatomical Sciences, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran., Dizaji Asl K; Department of Histopathology and Anatomy, Faculty of Medical Sciences, Tabriz Medical Sciences, Islamic Azad University, Tabriz, Iran., Mazloumi Z; Department of Medical Applied Cell Sciences, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran., Bahramloo M; Department of Medical Sciences, Student Research Committee, Tabriz Branch, Islamic Azad University, Tabriz, Iran., Norouzi N; Nursing Trauma Research Center, Kashan University of Medical Sciences, Kashan, Iran., Naderali E; Department of Anatomical Sciences, Maragheh University of Medical Sciences, Maragheh, Iran., Rafat A; Anatomical Sciences Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran. Rafata@tbzmed.ac.ir.
Jazyk: angličtina
Zdroj: Molecular biology reports [Mol Biol Rep] 2024 Nov 22; Vol. 52 (1), pp. 10. Date of Electronic Publication: 2024 Nov 22.
DOI: 10.1007/s11033-024-10106-6
Abstrakt: Infertility is a reproductive health problem in the male or female reproductive system. Traditional assisted reproductive technology (ART) has been unable to solve various cases of infertility for years. Clinical researchers have sought to treat infertility using new methods that are more effective and noninvasive than the old methods. Recently, Mesenchymal stem cells (MSCs) and MSCs-derived Exosomes (MSC-Exos) via paracrine activity play an important role in treating various causes of infertility and improving pregnancy outcomes. In this review, we focus on the roles of MSCs and MSC-Exos cell therapy in female infertility in the different types of female reproductive disorders.
Competing Interests: Declarations. Ethics approval: N.A. Consent to participate: N.A. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
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