Multimorbidity patterns in dementia and mild cognitive impairment.

Autor:	Valdevila Figueira JA; Faculty of Marketing and Communication, Universidad Ecotec, Guayaquil, Ecuador.; Research Network in Psychology and Psychiatry (GIPSI), Guayaquil, Ecuador.; Institute of Neurosciences, Junta de Beneficencia de Guayaquil, Guayaquil, Ecuador., Valdevila Santiesteban R; Research Network in Psychology and Psychiatry (GIPSI), Guayaquil, Ecuador., Carvajal Parra ID; Research Network in Psychology and Psychiatry (GIPSI), Guayaquil, Ecuador.; Institute of Neurosciences, Junta de Beneficencia de Guayaquil, Guayaquil, Ecuador., Benenaula Vargas LP; Faculty of Marketing and Communication, Universidad Ecotec, Guayaquil, Ecuador.; Research Network in Psychology and Psychiatry (GIPSI), Guayaquil, Ecuador., Ramírez A; Carrera de Psicología Clínica, Universidad Politécnica Salesiana, Cuenca, Ecuador., Leon-Rojas JE; Escuela de Medicina, Universidad de las Américas, Quito, Ecuador., Rodas JA; Research Network in Psychology and Psychiatry (GIPSI), Guayaquil, Ecuador.; Escuela de Psicología, Universidad Espíritu Santo, Samborondón, Ecuador.; School of Psychology, University College Dublin, Dublin, Ireland.
Jazyk:	angličtina
Zdroj:	Frontiers in psychiatry [Front Psychiatry] 2024 Nov 07; Vol. 15, pp. 1432848. Date of Electronic Publication: 2024 Nov 07 (Print Publication: 2024).
DOI:	10.3389/fpsyt.2024.1432848
Abstrakt:	Design: This is a retrospective cohort study. Setting: The study was conducted at the Instituto de Neurociencias de la Junta de Beneficencia de Guayaquil, a primary neuroscience institute in Ecuador. Participants: The study evaluated 425 participants diagnosed with Mild Cognitive Impairment (MCI) or dementia, out of which 272 individuals (mean age = 75 years; 164 female) presenting specific medical conditions were selected for analysis. Measurements: Data were collected on demographics, medical history, and neuropsychological assessment using the Neuropsi scale. Conditions such as Type 2 Diabetes Mellitus, hypertension, obesity, and history of traumatic brain injury were specifically noted. Results: Latent Class Analysis identified three distinct classes of patients: Unspecified Cognitive Deterioration, Dementia, and MCI. The three-class model provided the best fit, revealing varied morbidity patterns and highlighting the influence of vascular and metabolic conditions on cognitive decline. Notably, similarities in hypertension and diabetes prevalence between Dementia and MCI classes suggested shared risk factors. The study also found no significant age differences between the classes, indicating that age alone might not be the primary determinant in the progression of cognitive decline. Conclusions: The study underscores the complexity of dementia and MCI in an ageing Ecuadorian population, with vascular health playing a crucial role in cognitive impairment. These findings advocate for a holistic approach in managing dementia and MCI, emphasising the importance of addressing cardiovascular and metabolic health alongside neurocognitive care. The distinct morbidity patterns identified offer insights into tailored intervention strategies, highlighting the need for comprehensive, multidisciplinary care in dementia management. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Valdevila Figueira, Valdevila Santiesteban, Carvajal Parra, Benenaula Vargas, Ramírez, Leon-Rojas and Rodas.)
Databáze:	MEDLINE
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