To investigate endoscopic membranous nasolacrimal duct resection combined with retrograde lacrimal stent placement in the treatment of extremely inferior lacrimal duct obstruction.

Autor: Gan P; The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China. ganpuying@126.com., Ren Z; The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China., Xiong C; The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China., Yu J; The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China., Wang Y; The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China., Liao H; The Affiliated Eye Hospital, Jiangxi Medical College, Nanchang University, No. 463 Bayi Avenue, Nanchang City, 330006, Jiangxi Province, China. lhfzf@126.com.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2024 Nov 22; Vol. 14 (1), pp. 28925. Date of Electronic Publication: 2024 Nov 22.
DOI: 10.1038/s41598-024-80388-0
Abstrakt: To investigate the efficacy of endoscopic membranous nasolacrimal duct resection combined with retrograde lacrimal stent in the treatment of extremely inferior lacrimal duct obstruction. Retrospective cohort study at Nanchang University's Affiliated Eye Hospital. Experimental Group: Endoscopic membranous nasolacrimal duct resection combined with retrograde lacrimal stent implantation; Control group: Conventional endoscopic dacryocystorhinostomy combined with bicanalicular Silicone Stent implantation.The duration of the surgical procedure, postoperative comfort score, irrigation of the lacrimal passage after extubation, and Munk score of curative effect at six months post-operation were recorded. The data were quantified and analyzed using SPSS 26.0 statistical software. The symptoms of epiphora showed significant improvement following surgery. There were notable differences in operation time and postoperative comfort between the experimental group and the control group who underwent conventional endoscopic dacryocystorhinostomy (P < 0.05). However, there was no significant difference in efficacy and lacrimal duct irrigation after extubation or at six months post-operation (P > 0.05). The cure rate of the experimental group reached 70%, while the control group achieved a cure rate of 78%. Furthermore, the effective rate in the experimental group was found to be 81%, whereas it was 89% in the control group.No evident complications were observed in the experimental group. The combination of endoscopic membranous nasolacrimal duct resection and retrograde lacrimal stent reduces the invasiveness of the lacrimal duct structure, shortens the operation time, improves patient comfort, and achieves favorable therapeutic outcomes. This approach is recommended for patients with extremely Inferior lacrimal duct obstruction .
Competing Interests: Declarations. Competing interests: The authors declare no competing interests. Consent for publication: Written informed consent was obtained from the person for publication of his accompanying images in this manuscript. Ethical approval: Approval Statement: This research project has been approved by the Institutional Review Board (IRB) of The Affiliated Eye Hospital of Nanchang University. The IRB carefully reviewed the study protocol, ensuring that it meets ethical standards and safeguards the rights and welfare of all participants.The ethics approval number for this study was YLS20240415. Accordance Statement: The research methods and data analysis procedures have been designed to ensure compliance with scientific rigor and integrity. All ethical considerations have been addressed, and the work adheres to the principles of honesty, objectivity, and transparency. The authors affirm that the content of this manuscript is an accurate representation of the research conducted and complies with all applicable laws and regulations.
(© 2024. The Author(s).)
Databáze: MEDLINE
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