Congenital teratoma of the oral cavity - the largest personal series of cases.

Autor: da Silva Freitas R; Plastic Surgery Unit, Hospital de Clínicas, Federal University of Paraná, Craniofacial Surgeon - Assistance Center for Cleft Lip and Palate, Curitiba, Brazil. dr.renato.freitas@gmail.com.; Department of Plastic Surgery, Federal University of Paraná, General Carneiro Street, 181- 9th floor- Alto da Glória, Curitiba, Paraná, Brazil. dr.renato.freitas@gmail.com., Bernert BF; Plastic Surgery Unit, Hospital de Clínicas, Federal University of Paraná, Curitiba, Brazil., Guarezi Nasser IJ; Assistance Center for Cleft Lip and Palate, Curitiba, Brazil., Lupion FG; Assistance Center for Cleft Lip and Palate, Curitiba, Brazil., Angeli-Freitas E; Faculdade Evangélica Mackenzie do Paraná, Curitiba, Brazil., Grande CV; Hospital de Clínicas, Federal University of Paraná and Assistance Center for Cleft Lip and Palate, Curitiba, Brazil.
Jazyk: angličtina
Zdroj: Oral and maxillofacial surgery [Oral Maxillofac Surg] 2024 Nov 22; Vol. 29 (1), pp. 13. Date of Electronic Publication: 2024 Nov 22.
DOI: 10.1007/s10006-024-01307-1
Abstrakt: Purpose: The objective of this study is to present the largest personal series of oral teratomas already published in English literature and discuss the diagnosis, neonatal management, and surgical treatment of this disorder.
Method: The study included patients treated by the senior author (RSF) between 2004 and 2023. Data were collected regarding prenatal evaluation, perinatal approach, surgical management, evolution, and treatment of secondary deformities. In addition, we performed a literature review on the topic.
Results: Twelve patients with oral teratoma were included in this study. Seven cases did not have been submitted to any previous treatment, and five cases had already undergone some treatment in another institution. Four cases were diagnosed as epignathus (33.3%), two as true teratomas (16.6%), four as teratoid teratomas (33.3%), one as dermoid teratoma (8.3%) and one as fetus in fetus (8.3%). All patients, except for one, had the tumor surgically removed with good evolution. There was one case of recurrence, successfully operated. The most frequently associated comorbidity was 0-14 fissure, present in 66% of the cases.
Conclusion: The experience of our twelve cases indicates that prenatal diagnosis, associated with good multidisciplinary planning of the delivery care, and complete resection of the masses reveal high success rates in the treatment of this pathology.
Clinical Trial Number: This study was performed in line with the principles of the declaration of Helsinki. Approval was granted by the Ethics Committee of Federal University of Paraná - 47102421.2.0000.5225.
Competing Interests: Declarations. Ethical approval: This study was performed in line with the principles of the declaration of Helsinki. Approval was granted by the Ethics Committee of Federal University of Paraná − 47102421.2.0000.5225. Informed consent was obtained from all individual participants or legal responsible included in the study. The authors affirm that human research participants provided informed consent for publication of the images in Figs. 1, 2, 3 and 4. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Databáze: MEDLINE