Unmasking Tinea Incognito: Case Study, Insights Into the Pathogenesis, and Recommendations.

Autor: Gallegos Espadas D; Internal Medicine, Hospital Regional Elvia Carrillo Puerto, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mérida, MEX.; Internal Medicine, Facultad de Medicina de la Universidad Autónoma de Yucatán, Mérida, MEX., Martínez-Ortega JI; Dermatology, Dermatology Institute of Jalisco, Zapopan, MEX.; Histology, Autonomous University of Nuevo León, Monterrey, MEX., Garcia Hernandez DA; Internal Medicine, 'Dr. Antonio González Guevara' Civil Hospital, Nayarit, MEX., Sánchez Mendieta CP; Internal Medicine, Hospital Regional Elvia Carrillo Puerto, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mérida, MEX.; Internal Medicine, Facultad de Medicina de la Universidad Autónoma de Yucatán, Mérida, MEX., Fernández-Reyna I; Mycology, Dermatology Center of Yucatán, Mérida, MEX.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Oct 21; Vol. 16 (10), pp. e72042. Date of Electronic Publication: 2024 Oct 21 (Print Publication: 2024).
DOI: 10.7759/cureus.72042
Abstrakt: Tinea incognito (TI) is a dermatophyte infection that often presents atypically due to the inappropriate use of corticosteroids or other immunosuppressive treatments, complicating its diagnosis and management. This case report describes a 29-year-old American Indian (Maya) female from Yucatán, Mexico, initially diagnosed with inverse psoriasis and treated with topical corticosteroids. Over several months, her condition deteriorated, with lesions spreading and worsening, ultimately revealing TI. The misdiagnosis was attributed to the masking effects of corticosteroids, which suppressed the immune response and facilitated fungal dissemination. The case underscores the diagnostic difficulties of TI, particularly when treatments exacerbate rather than alleviate the condition. Key to diagnosis is the combination of patient history, mycological testing, and clinical examination. The study also highlights the role of chronic glucocorticoid use in impairing antifungal immunity by reducing crucial cytokines like IL-17 and IFN-γ, leading to persistent fungal infections. Furthermore, addressing underlying conditions such as obesity, insulin resistance, and diabetes is essential for effective management. Timely and accurate identification of TI, coupled with appropriate treatment, is critical to prevent complications and improve patient outcomes.
Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Gallegos Espadas et al.)
Databáze: MEDLINE