Bilateral Compartment Syndrome Affecting the Upper Limbs in a Patient With Chronic Myeloid Leukemia.
| Autor: | Varadhan A; Emergency Medicine, Peterborough City Hospital, Peterborough, GBR., Bagavandoss A; Internal Medicine, Peterborough City Hospital, Peterborough, GBR., Edmunds CT; Critical Care Medicine, Peterborough City Hospital, Peterborough, GBR., Oyibo SO; Diabetes and Endocrinology, Peterborough City Hospital, Peterborough, GBR. |
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| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Nov 20; Vol. 16 (11), pp. e74104. Date of Electronic Publication: 2024 Nov 20 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.74104 |
| Abstrakt: | A 70-year-old male patient who had recently been recently diagnosed with chromic myeloid leukemia (CML) presented to the emergency department with bilateral upper limb pain and swelling. Examination of his upper limbs revealed features suggestive of compartment syndrome. Blood investigations demonstrated anaemia, rhabdomyolysis and renal function impairment. Because of the rapid fall in hemoglobin levels, he required clotting factors and blood product resuscitation. Compartment pressure measurements were elevated, confirming the diagnosis of bilateral acute compartment syndrome secondary to bleeding. Initial investigations demonstrated low factor XIII levels. Once stabilized, he underwent bilateral fasciotomies but required intensive care management post-surgery, including ongoing blood product resuscitation and renal replacement therapy. Levels of factor XIII continued to fall. Although there have been reported cases of acute leukaemia involving factor XIII deficiency, reports of chronic leukaemia involving factor XIII deficiency are rare. This case provides key learning of a known complication of acute leukaemia and highlights a rare surgical complication of factor XIII deficiency. Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Varadhan et al.) |
| Databáze: | MEDLINE |
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