The role of New World vultures as carriers of environmental antimicrobial resistance.

Autor: Tallon AK; Helmholtz Institute for Functional Marine Biodiversity at the University of Oldenburg (HiFMB), Ammerländer, Heerstrasse 231, 26121, Oldenburg, Germany. anya.tallon@gmail.com., Smith RK; USDA-ARS, Genetics and Sustainable Agriculture Unit, 150 Twelve Lane, Mississippi State, MS, 39762-5367, USA., Rush S; Department of Wildlife, Fisheries, and Aquaculture, Mississippi State University, P.O. Box 9690, Mississippi State, MS, 39762, USA., Naveda-Rodriguez A; Department of Wildlife, Fisheries, and Aquaculture, Mississippi State University, P.O. Box 9690, Mississippi State, MS, 39762, USA., Brooks JP; USDA-ARS, Genetics and Sustainable Agriculture Unit, 150 Twelve Lane, Mississippi State, MS, 39762-5367, USA. john.brooks@usda.gov.
Jazyk: angličtina
Zdroj: BMC microbiology [BMC Microbiol] 2024 Nov 20; Vol. 24 (1), pp. 487. Date of Electronic Publication: 2024 Nov 20.
DOI: 10.1186/s12866-024-03621-w
Abstrakt: Background: Although antibiotics have significantly improved human and animal health, their intensive use leads to the accumulation of antimicrobial resistance (AMR) in the environment. Moreover, certain waste management practices create the ideal conditions for AMR development while providing predictable resources for wildlife. Here, we investigated the role of landfills in the potentiation of New World vultures to disseminate environmental AMR. We collected 107 samples (soil, water, and feces) between 2023 and 2024, in different bird use sites (roosts, landfills and boneyards).
Results: We isolated enterococci (EN), Escherichia coli (EC), and Salmonella spp. (SM), performed antibiotic susceptibility tests, and quantified the presence of antibiotic resistance genes (ARGs) within all samples. We identified EN, EC, and SM, in 50, 37, and 26 samples, from the three vulture use areas, respectively. AMR was mainly to aminoglycoside, cephalosporin, and tetracycline, and the prevalence of multidrug resistance (MDR) was 5.3% (EC), 78.2% (EN), and 17.6% (SM). Variations in bacterial abundance and AMR/MDR profiles were found based on the season, use site, and sample types, which was corroborated by ARG analyses.
Conclusions: Our study suggests that landfills constitute a source of zoonotic pathogens and AMR for wildlife, due to readily available refuse input. Using non-invasive molecular methods, we highlight an often-ignored ecosystem within the One Health paradigm.
Competing Interests: Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.
(© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)
Databáze: MEDLINE
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