A Case Involving Linezolid-induced Fatal Lactic Acidosis and Pancytopenia.
| Autor: | Mehta K; Associate Professor, Department of Respiratory Medicine, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth University, Pune, Maharashtra, India., Gandhi R; Resident, Department of Respiratory Medicine, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth University, Pune, Maharashtra, India, Corresponding Author., Ansari IS; Resident, Department of Respiratory Medicine, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth University, Pune, Maharashtra, India., Barthwal MS; Professor and HOD, Department of Respiratory Medicine, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth University, Pune, Maharashtra, India. |
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| Jazyk: | angličtina |
| Zdroj: | The Journal of the Association of Physicians of India [J Assoc Physicians India] 2024 Nov; Vol. 72 (11), pp. e45-e46. |
| DOI: | 10.59556/japi.72.0735 |
| Abstrakt: | We present a case of a 77-year-old female diagnosed with multidrug-resistant (MDR) pulmonary tuberculosis (PTB), on all oral longer regimen [according to Indian Programmatic Management of Drug Resistant Tuberculosis (PMDT) guidelines] for a month. She presented with nausea, vomiting, worsening of breathlessness for a week, pancytopenia, and gradually increasing lactate levels. Various causes of lactic acidosis including metabolic, septic, and hypoxic were ruled out. Despite our dedicated efforts, she tragically passed away due to severe lactic acidosis, a complication associated with linezolid treatment. (© Journal of the Association of Physicians of India 2024.) |
| Databáze: | MEDLINE |
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