Heart failure and cardiomyopathy mortality trends and disparities among obese populations: A 20-year United States study.

Autor: Yeo YH; Department of Internal Medicine/ Pediatrics, William Beaumont University Hospital, Royal Oak, MI, USA., San BJ; AIMST University, Malaysia., Ahmad E; Department of Internal Medicine, William Beaumont University Hospital, Royal Oak, MI, USA., Tan MC; Department of Internal Medicine, New York Medical College at Saint Michael's Medical Center, Newark, NJ, USA; Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ, USA., Sin YM; AIMST University, Malaysia., Jani M; Advanced Heart Failure and Transplant Cardiology Section, Spectrum Health, Grand Rapids, MI, USA., Bloomingdale RJ; Department of Cardiovascular Medicine, William Beaumont University Hospital, Royal Oak, MI, USA. Electronic address: richard.bloomingdale@corewellhealth.org.
Jazyk: angličtina
Zdroj: Preventive medicine [Prev Med] 2025 Jan; Vol. 190, pp. 108179. Date of Electronic Publication: 2024 Nov 17.
DOI: 10.1016/j.ypmed.2024.108179
Abstrakt: Objective: Our study aimed to assess the heart failure/cardiomyopathy-related population-level mortality trends among patients with obesity in the United States and disparities across demographics.
Methods: We queried the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research database among adults aged ≥25 from 1999 to 2019. Heart failure/cardiomyopathy were listed as the main causes of death, with obesity as a contributing cause. We calculated age-adjusted mortality rates (AAMR) per 100,000 individuals and estimated the average annual percent change (AAPC). We also evaluated the social vulnerability of United States counties (2014-2018).
Results: There were 29,334 deaths related to heart failure/cardiomyopathy among patients with comorbid obesity. The overall AAMR increased from 0.41 in 1999 to 0.94 in 2019, with an AAPC of 3.78 (95 % CI, 3.41-4.14). The crude mortality rate increase for heart failure/cardiomyopathy was greater in individuals with comorbid obesity than in those without. Males had a higher AAMR than females (0.78 vs 0.55). African Americans also had higher AAMR than Whites (1.35 vs 0.62). The AAMR was higher in rural areas than in urban regions (0.76 vs 0.66). The overall AAMR was higher in counties with social vulnerability index-Quartile 4 (SVI-Q4) (most vulnerable) (1.08) compared to SVI-Q1 (least vulnerable) (0.63) with a risk ratio of 1.71 (95 % CI: 1.61-1.83).
Conclusion: Heart failure/cardiomyopathy mortality in individuals with comorbid obesity was rising. Males, African Americans, and individuals from rural regions had higher AAMR than their counterparts.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: