Honeybee Venom: A Potential Source of Anticancer Components.

Autor: Khor SXY; School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, 47500 Subang Jaya, Selangor Darul Ehsan, Malaysia., Khongphinitbunjong K; School of Science, Mae Fah Luang University, Chiang Rai57100, Thailand., Owatworakit A; School of Science, Mae Fah Luang University, Chiang Rai57100, Thailand.; Microbial Product and Innovation Research Group, Mae Fah Luang University, Chiang Rai57100, Thailand., Mah SH; School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, 47500 Subang Jaya, Selangor Darul Ehsan, Malaysia.; School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand., Tang YQ; School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, 47500 Subang Jaya, Selangor Darul Ehsan, Malaysia.; School of Science, Mae Fah Luang University, Chiang Rai57100, Thailand.
Jazyk: angličtina
Zdroj: Protein and peptide letters [Protein Pept Lett] 2024 Nov 15. Date of Electronic Publication: 2024 Nov 15.
DOI: 10.2174/0109298665339355241008104141
Abstrakt: Cancer is a deadly disease that has claimed millions of lives worldwide. Traditional cancer treatments, such as chemotherapy and radiation, have been used for many years but have become less favored due to drug resistance, lack of tumor selectivity, high costs, and various side effects, such as fatigue and hair loss. Many studies have reported that animal venoms, such as those from snakes, scorpions, and bees, contain bioactive peptides that can be synthesized into anti-- cancer peptides (ACPs), which offer a potential alternative to traditional cancer therapies. Apitherapy is an area of growing interest for the development of new cancer treatments using bee venom, which is a complex mixture of biologically active peptides, enzymes, bioactive amines, and nonpeptide components that have been found to have anti-cancer properties. By leveraging these bioactive peptides, researchers could develop ACPs that are more targeted towards cancer cells, reducing the risk of adverse side effects and improving patient outcomes. The use of bee venom components in targeting cancer could provide a more selective, effective, and affordable approach to cancer therapy. While further research is needed, the potential benefits of using bee venom components in cancer therapy are significant and could help improve the lives of cancer patients worldwide. This study aims to review the components of bee venom as potential cancer treatments.
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Databáze: MEDLINE