DNA Duplex Containing Ag + -Mediated Cytosine-Cytosine Base Pairs as a Catalyst Precursor for the 4-Nitrophenol Reduction with NaBH 4 .

Autor: Dairaku T; Integrated Center for Science and Humanities, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima 960-1295, Japan.; Hydrogen Energy Research Institute, Fukushima University, 1 Kanayagawa, Fukushima City, Fukushima 960-1296, Japan., Nozawa-Kumada K; Interdisciplinary Research Center for Catalytic Chemistry, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8565, Japan., Ono T; School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomita-machi, Koriyama, Fukushima 963-8611, Japan., Yoshida K; School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomita-machi, Koriyama, Fukushima 963-8611, Japan., Kashiwagi Y; School of Pharmaceutical Sciences, Ohu University, 31-1 Misumido, Tomita-machi, Koriyama, Fukushima 963-8611, Japan., Tanaka Y; Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan., Kondo J; Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan., Tanabe M; Integrated Center for Science and Humanities, Fukushima Medical University, 1 Hikarigaoka, Fukushima City, Fukushima 960-1295, Japan.; Hydrogen Energy Research Institute, Fukushima University, 1 Kanayagawa, Fukushima City, Fukushima 960-1296, Japan.
Jazyk: angličtina
Zdroj: Inorganic chemistry [Inorg Chem] 2024 Dec 02; Vol. 63 (48), pp. 22845-22855. Date of Electronic Publication: 2024 Nov 18.
DOI: 10.1021/acs.inorgchem.4c03830
Abstrakt: Catalytic applications of DNA duplexes containing Ag + -mediated cytosine-cytosine base pairs (C-Ag + -C) have not been well investigated. In this study, we demonstrate a novel approach for forming highly active DNA-capped Ag nanoparticle (DNA-AgNP) catalysts for the reduction of 4-nitrophenol (4-NP) using sodium borohydride (NaBH 4 ). This approach is based on the in situ generation of DNA-AgNPs from DNA duplexes containing C-Ag + -C (DNA duplex-Ag + ). UV-vis spectroscopic analysis suggests that the DNA duplex-Ag + complex acts as an excellent catalyst precursor for 4-NP reduction with NaBH 4 . Transmission electron microscopy observations of the reaction solution after the 4-NP reduction reaction using DNA duplex-Ag + provided detailed experimental insights into the mechanism of the catalytic activity of DNA duplex-Ag + for 4-NP reduction. In the reaction solution, DNA-AgNPs were initially formed (DNA duplex-Ag + + NaBH 4 → DNA-AgNPs) and then served as water-soluble catalysts for 4-NP reduction. Notably, the catalytic properties of the DNA-AgNPs generated in situ were affected by the DNA strand length and sequence. The properties of DNA duplex-Ag + may provide a new application of DNA molecules containing metallobase pairs as water-soluble catalyst precursors.
Databáze: MEDLINE
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