The Gray Area of Sarcoidosis and Tuberculosis: A Diagnostic Enigma.

Autor:	Meshram SB; Respiratory Medicine, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND., Gandhi RP; Respiratory Medicine, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND., Reddy GHV; Respiratory Medicine, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Oct 18; Vol. 16 (10), pp. e71763. Date of Electronic Publication: 2024 Oct 18 (Print Publication: 2024).
DOI:	10.7759/cureus.71763
Abstrakt:	This case report presents a challenging diagnostic enigma, where a 29-year-old male patient presented with symptoms and signs favoring both tuberculosis (TB) and sarcoidosis. The patient's plain chest radiograph showed bilateral hilar opacities, while a contrast-enhanced computed tomography (CECT) scan revealed multiple mediastinal and hilar lymph nodes. Histopathology of a mediastinal lymph node biopsy showed necrotizing granulomatous inflammation, favoring TB. However, the patient's symptoms did not resolve with antitubercular treatment, and further investigations revealed a working diagnosis of pulmonary sarcoidosis. The patient's symptoms improved with corticosteroid therapy, and subsequent plain chest radiographs and high-resolution computed tomography (HRCT) scans showed near complete resolution of lung infiltrates. This case highlights the importance of careful evaluation and interpretation of biopsy results and the use of advanced diagnostic techniques to diagnose and differentiate between TB and sarcoidosis accurately. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Meshram et al.)
Databáze:	MEDLINE
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