A Comprehensive Review of Recent Trends in Surgical Approaches for Epilepsy Management.

Autor:	Sabzvari T; Medical School, McMaster University, Hamilton, CAN., Aflahe Iqbal M; General Practice, Muslim Educational Society (MES) Medical College Hospital, Perinthalmanna, IND.; General Practice, Naseem Medical Centre, Doha, QAT., Ranganatha A; Surgery, Jagadguru Jayadeva Murugarajendra (JJM) Medical College, Davangere, IND., Daher JC; Medicine, Lakeland Regional Health, Lakeland, USA.; Medicine, Universidad de Ciencias Médicas Andrés Vesalio Guzmán, San Jose, CRI., Freire I; General Practice, Universidad Central del Ecuador, Quito, ECU., Shamsi SMF; Medical School, Alfaisal University College of Medicine, Riyadh, SAU., Paul Anthony OV; Surgery, OO Bogomolets National Medical University, Kyiv, UKR., Hingorani AG; Medicine and Surgery, Mahatma Gandhi Mission (MGM) Medical College and Hospital, Mumbai, IND., Sinha AS; Surgery, Kasturba Medical College, Manipal, Manipal, IND., Nazir Z; Internal Medicine, Combined Military Hospital, Quetta, PAK.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Oct 17; Vol. 16 (10), pp. e71715. Date of Electronic Publication: 2024 Oct 17 (Print Publication: 2024).
DOI:	10.7759/cureus.71715
Abstrakt:	Epilepsy is a neurological disorder that affects millions of people worldwide, with a significant proportion of patients experiencing drug-resistant epilepsy, where seizures remain uncontrolled despite medical treatment. This review evaluates the latest surgical techniques for managing epilepsy, focusing on their effectiveness, safety, and the ongoing challenges that hinder their broader adoption. We explored various databases including PubMed, Google Scholar, and Cochrane Library to look for relevant literature using the following keywords: Epilepsy, Resective Surgery, Corpus Collectumy, and Antiepileptic Drugs. A total of 54 relevant articles were found and thoroughly explored. Recent advancements in surgical interventions include resective procedures such as anterior temporal lobectomy, corpus callosotomy, and hemispherectomy, which have been particularly effective in reducing seizures for specific types of epilepsy. Minimally invasive techniques, including laser interstitial thermal therapy and focused ultrasound, are increasingly being used, offering promising outcomes for certain patient groups. Additionally, neuromodulation methods such as deep brain stimulation, vagus nerve stimulation, and responsive neurostimulation provide alternative treatment options, especially for patients who are not suitable candidates for resective surgery. Despite these advancements, the full potential of epilepsy surgery is often underutilized due to various challenges. Inconsistent referral practices, a lack of standardized surgical protocols, and significant socioeconomic barriers continue to limit access to these procedures. Addressing these issues through improved referral processes, better education for healthcare providers and patients, and ensuring equitable access to advanced surgical treatments is crucial for optimizing patient outcomes. Future research should focus on overcoming these barriers and assessing long-term outcomes to further enhance the care of patients with epilepsy. Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Sabzvari et al.)
Databáze:	MEDLINE
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