No sex differences in systemic metabolic responses to acute sprint interval training performed after an oral 75-g glucose load in adults with excess adiposity.

Autor: Ramírez-Vélez R; Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain; CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain; Facultad de Ciencias de la Educación, Unidad Central del Valle del Cauca (UCEVA), Túlua, Colombia. Electronic address: robin640@hotmail.com., Carrillo-Arango HA; Grupo de Investigación en Deporte de Rendimiento (GRINDER), Programa de Educación Física y Deporte, Universidad del Valle, Cali, Colombia. Electronic address: hugo.carrillo@correounivalle.edu.co., Atencio-Osorio MA; Grupo de Investigación en Deporte de Rendimiento (GRINDER), Programa de Educación Física y Deporte, Universidad del Valle, Cali, Colombia. Electronic address: miguel.atencio@correounivalle.edu.co., López-Álban CA; Grupo de Investigación en Deporte de Rendimiento (GRINDER), Programa de Educación Física y Deporte, Universidad del Valle, Cali, Colombia; Zoe h&f Centro Para la Investigación En Salud y Rendimiento Humano, Cali, Colombia. Electronic address: carlos.alban@correounivalle.edu.co., Calderon-González JC; Facultad de Ciencias de la Educación, Unidad Central del Valle del Cauca (UCEVA), Túlua, Colombia. Electronic address: jcalderon@uceva.edu.co., Morales-Álamo D; Department of Physical Education and Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain. Electronic address: moralesalamo.d@gmail.com., Izquierdo M; Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), Instituto de Investigación Sanitaria de Navarra (IdiSNA), Pamplona, Spain; CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: mikel.izquierdo@gmail.com., Correa-Rodríguez M; Department of Nursing, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain. Electronic address: macoro@ugr.es.
Jazyk: angličtina
Zdroj: Clinical nutrition ESPEN [Clin Nutr ESPEN] 2024 Nov 17; Vol. 65, pp. 25-35. Date of Electronic Publication: 2024 Nov 17.
DOI: 10.1016/j.clnesp.2024.11.005
Abstrakt: Background & Aims: Research exploring sex-based variations in responses to acute sprint interval training (SIT) remains limited. This study aimed to examine the impact of biological sex on the systemic metabolic response to SIT. We hypothesized that acute metabolic responses to SIT would differ between males and females.
Methods: Sedentary adults (15 males; 14 females) with excess adiposity (defined as body fat >30 %) were matched for age (32.8 ± 7.5 vs. 29.5 ± 6.5 years) and body fat mass (33.0 ± 2.9 vs. 33.2 ± 2.8 %). Following a 75-g glucose load, participants were randomly allocated to either a control (resting) or SIT trial (8 × 30 s of "all-out" cycling at a resistance of 0.075 % W kg -1 of muscle mass, interspersed with 1 min of recovery). Parameters assessed included respiratory quotient (RQ), resting energy expenditure (REE), substrate utilization rates (fat and carbohydrate), total energy output, and blood lactate and glucose levels. These were collected during fasting and at 60, 120, and 240 min post-glucose load, with the area under the curve (AUC) calculated for both trials.
Results: An interaction was observed in time (P = 0.012) and trial (P < 0.001) for RQ; however, there was no significant interaction between sex × trial (P = 0.818). Males exhibited higher mean REE values than females in both conditions. Nevertheless, AUC analysis showed no significant interaction between sex and trial (P = 0.562). A significant trial × time relationship was found for fat and carbohydrate percentage contributions (P < 0.001). Post-SIT, AUCs for fat contribution (g min -1 and mg kg - 1  min -1 ) to energy expenditure increased in both sexes compared with resting (P < 0.05), with differences noted among trials over time (P < 0.001). Blood lactate levels also increased similarly post-SIT in both sexes (P < 0.05), without a significant sex × trial interaction (AUC, P = 0.798).
Conclusions: These data demonstrate that exercise differed between the sexes and did not support the premise that acute metabolic responses to SIT would vary between males and females.
Competing Interests: Declaration of competing interest The authors declare that no conflicts of interest could be perceived as prejudicing the impartiality of the reported research.
(Copyright © 2024 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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