Effects of multidisciplinary therapy on energy balance, inflammation, and metabolic diseases in adolescents with obesity: A narrative review.

Autor: Dâmaso AR; Post-Graduate Program of Nutrition-Federal University of São Paulo-Paulista Medicine School-UNIFESP-EPM, São Paulo, Brazil.; Brazilian Association for the Study of Obesity and Metabolic Syndrome-ABESO, São Paulo, Brazil., Masquio DCL; Post-Graduate Program of Nutrition-Federal University of São Paulo-Paulista Medicine School-UNIFESP-EPM, São Paulo, Brazil.; Centro Universitário São Camilo-Post-Graduate Program of Professional Nutrition: from Birth to Adolescence - Undergraduate course in Nutrition and Medicine, São Paulo, Brazil., Campos RMDS; Post-Graduate Program of Interdisciplinary in Health Sciences-Federal University of São Paulo-Campus Baixada Santista-UNIFESP, Santos, Brazil., Corgosinho FC; Nutrition Faculty-Federal University of Goiás-UEGo, Goiânia, Goiás, Brazil., Cercato C; Brazilian Association for the Study of Obesity and Metabolic Syndrome-ABESO, São Paulo, Brazil.; University of São Paulo-Medicine School-Post-Graduate Program of Endocrinology, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2024 Dec; Vol. 1542 (1), pp. 25-50. Date of Electronic Publication: 2024 Nov 16.
DOI: 10.1111/nyas.15251
Abstrakt: Obesity is a consequence of multiple factors, including genetics, lifestyle and nutritional choices, physical activity, sleep duration, screen time, and mood disorders. These behavioral elements can impair the regulation of energy balance and obesity management that link obesity to a constellation of chronic conditions that lead to a high prevalence of cardiometabolic risk factors, metabolic syndrome, and nonalcoholic fatty liver disease. Multidisciplinary therapy is defined as an approach delivered by a multidisciplinary-trained health team covering at least two components of behavior, physical activity/exercise, dietary habits, and/or psychological counseling associated with clinical interventions. This narrative review summarizes the effects of multidisciplinary therapy on neuroendocrine regulation of energy balance, inflammatory biomarkers, cardiometabolic risk factors, metabolic syndrome, nonalcoholic fatty liver diseases, behavior, and quality of life. We found that multidisciplinary therapy, including medical, nutritional, exercise, and behavioral counseling, and/or education, was useful for addressing outcomes such as visceral adiposity, neuroendocrine regulation of energy balance, inflammatory biomarkers, cardiometabolic risk factors, nonalcoholic fatty liver disease, and metabolic syndrome. The effects were mediated by improvements in neuroendocrine regulation of energy balance, downregulation of the pro-inflammatory states, and a reduction in comorbidities. Multidisciplinary therapy also improved mood disorders and quality of life.
(© 2024 The Author(s). Annals of the New York Academy of Sciences published by Wiley Periodicals LLC on behalf of The New York Academy of Sciences.)
Databáze: MEDLINE
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