Comparison of responders and nonresponders with knee osteoarthritis after transcranial direct current stimulation.

Autor: Park J; College of Nursing, The University of Arizona, Tucson, AZ, USA., Tong H; Department of Statistics Tallahassee, Florida State University, Tallahassee, FL, USA., Kang Y; Department of Statistics Tallahassee, Florida State University, Tallahassee, FL, USA., Miao H; College of Nursing Tallahassee, Florida State University, Tallahassee, FL, USA., Lin L; College of Public Health Epidemiology and Biostatistics Department, The University of Arizona, Tucson, AZ, USA., Fox RS; College of Nursing, The University of Arizona, Tucson, AZ, USA., Telkes I; Department of Neurosurgery, The University of Arizona College of Medicine, Tucson, AZ, USA.; College of Medicine Department of Neurosurgery, The University of Arizona, Tucson, AZ, USA., Martorella G; College of Nursing Tallahassee, Florida State University, Tallahassee, FL, USA., Ahn H; College of Nursing, The University of Arizona, Tucson, AZ, USA.
Jazyk: angličtina
Zdroj: Pain management [Pain Manag] 2024 Nov 16, pp. 1-12. Date of Electronic Publication: 2024 Nov 16.
DOI: 10.1080/17581869.2024.2429943
Abstrakt: Aim: The study compared responders and nonresponders to transcranial direct current stimulation (tDCS) regarding clinical pain outcomes in knee osteoarthritis (OA) patients.
Patients and Methods/materials: Sixty participants received home-based active tDCS, and clinical pain outcomes were compared between responders and nonresponders.
Results: Latent class growth analyses classified 41 participants as responders and 19 as nonresponders. Responders showed significantly greater decreases in pain intensity from baseline to post intervention than nonresponders ( p  < .001). Participants with higher BMI ( p  = .02) and weight ( p  = .005) were more likely to respond, while no significant sociodemographic differences were found.
Conclusions: Identifying characteristics of nonresponsive tDCS subgroups can tailor treatments for each group.
Clinical Trial Registration: www.clinicaltrials.gov identifier is NCT04016272.
Databáze: MEDLINE