Assessment of Changes in Vascular Density in the Layers of the Eye in Patients With Parkinson's Disease.
| Autor: | Bilgin Ş; Department of Neurology, Health Sciences University Tepecik Training and Research Hospital, Izmir, Turkey., Uysal HA; Department of Neurology, IEU Medicalpoint Hospital, Izmir, Turkey., Bilgin S; Department of Ophthalmology, IEU Medicalpoint Hospital, Izmir, Turkey., Yaka EC; Department of Neurology, Health Sciences University Tepecik Training and Research Hospital, Izmir, Turkey., Küsbeci ÖY; Department of Neurology, IEU Medicalpoint Hospital, Izmir, Turkey., Şener U; Department of Neurology, Health Sciences University Tepecik Training and Research Hospital, Izmir, Turkey. |
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| Jazyk: | angličtina |
| Zdroj: | Annals of neurosciences [Ann Neurosci] 2024 Sep 03, pp. 09727531241259841. Date of Electronic Publication: 2024 Sep 03. |
| DOI: | 10.1177/09727531241259841 |
| Abstrakt: | Background: The retina is affected by Parkinson's disease (PD). Purpose: We aimed to assess the anatomical and vascular deterioration of the retina in PD. Methods: Sixty-six patients with PD and 66 healthy volunteers were evaluated in this study. Choriocapillaris vessel density (CCVD), superficial vascular density (SVD), deep vascular densities (DVD), central macular thickness (CMT), retinal nerve fibre layer (RNFL), ganglionic cell layer (GCL), and choroidal thickness (CT) were assessed. Results: RNFL, GCL, CMT, and CT were thinner than in HC, and also the differences between the groups were statistically significant ( P < .05). SVD and DVD were not statistically different between the groups ( P > .05). There was a decrease in vascular density in all quadrants of the choriocapillary layer. The decrease in vascular density was statistically significant in the nasal, inferior and central quadrants ( P < .05). Conclusion: These results supported vascular thinning in the choroidal layer. Also showed that vascular and neural layers were affected together. It could help clinicians in the follow-up of Parkinson's patients. Competing Interests: The authors declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article. (© The Author(s) 2024.) |
| Databáze: | MEDLINE |
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